Assessing vitamin D status: time for a rethink?

GD Carter, KW Phinney - Clinical chemistry, 2014 - academic.oup.com
Vitamin D status is universally assessed by measuring circulating total 25-hydroxyvitamin D
[25 (OH) D] 3, the sum of 25 (OH) D3 and 25 (OH) D2. However, despite the widespread …

Variability in vitamin D assays impairs clinical assessment of vitamin D status

JKC Lai, RM Lucas, E Banks… - Internal medicine …, 2012 - Wiley Online Library
Abstract Background: Measuring serum 25 (OH) D concentration is common in clinical
practice despite the questionable reliability of assays. Aims: The aim of the present study …

[HTML][HTML] Assessment of vitamin D status–a changing landscape

M Herrmann, CJL Farrell, I Pusceddu… - Clinical Chemistry and …, 2017 - degruyter.com
In recent years it has been shown that vitamin D deficiency is associated with an increased
incidence as well as the progression of a broad range of diseases including osteoporosis …

Measurement of vitamin D for epidemiologic and clinical research: shining light on a complex decision

AMZ Jukic, AN Hoofnagle… - American journal of …, 2018 - academic.oup.com
Vitamin D is a fat-soluble vitamin that is synthesized in the skin with exposure to sunlight or
is ingested from dietary supplements or food. There has been a dramatic increase in …

Towards a personalized assessment of vitamin D status

M Herrmann - Clinical Chemistry and Laboratory Medicine (CCLM), 2020 - degruyter.com
The growing interest in vitamin D has stimulated intensive research activities aiming to
address unresolved analytical, clinical and physiological aspects of vitamin D [1–4]. This …

Vitamin D binding protein and 25-hydroxyvitamin D levels: emerging clinical applications

NK Jassil, A Sharma, D Bikle, X Wang - Endocrine Practice, 2017 - Elsevier
The precursor of the active form of vitamin D, 25-hydroxyvitamin D (25 (OH) D), is
recognized as the optimal indicator of vitamin D status. Vitamin D3 undergoes conversion …

Critical evaluation of assays for vitamin D status

FG Lorencio, I Blanco-Navarro… - Current Opinion in …, 2013 - journals.lww.com
Despite the improvement in the analytical imprecision between methods and laboratories
over the last years, the reported prevalence of vitamin D deficiency in a given population still …

Significance of serum 24, 25-dihydroxyvitamin D in the assessment of vitamin D status: a double-edged sword?

KD Cashman, A Hayes, K Galvin, J Merkel… - Clinical …, 2015 - academic.oup.com
Abstract BACKGROUND 24, 25-Dihydroxyvitamin D [24, 25 (OH) 2D] in serum may be both
a nuisance and nutritionally valuable. METHODS We investigated the impact of 24, 25 (OH) …

Free or total 25OHD as marker for vitamin D status?

R Bouillon - Journal of Bone and Mineral Research, 2016 - academic.oup.com
(DBP). Why should this interest the readers of JBMR? Clinicians and even laypeople are
very familiar with the use of serum 25OHD concentrations as the most reliable marker of the …

Clinical, research, and public health implications of poor measurement of vitamin D status

RM Lucas, S Gorman, L Black… - Journal of AOAC …, 2017 - academic.oup.com
There is widespread concern about the high prevalence of vitamin D deficiency amid
evidence to support that such a state may increase the risk of a wide range of adverse health …