Transient receptor potential vanilloid 4 (TRPV4) is a non-selective mechanosensitive ion
channel expressed by various macrophage populations. Recent reports have characterized …

New Findings What is the topic of this review? In this concise review, we highlight insights
into the role of transient receptor potential, vanilloid type 4 (TRPV4) ion channels in the …

There is mounting evidence that the vanilloid (capsaicin) receptor; transient receptor
potential channel, vanilloid subfamily member 1 (TRPV1), is subjected to multiple interacting …

Methods: We developed TRPV4-knockout (TRPV4-KO) rats and assessed the effects of
Trpv4 gene deficiency in a monoiodoacetate (MIA)-induced OA pain model (MIA rats) by …

Background: Musculoskeletal pain is a condition that affects bones, muscles, and tendons
and is present in various diseases and/or clinical conditions. This type of pain represents a …

Little is known about the regulation of arthritis severity and joint damage in rheumatoid
arthritis (RA). Fibroblast-like synoviocytes (FLS) have a central role in joint damage and …

The transient receptor potential channel vanilloid type 1 (TRPV1) is a non-selective cation
channel expressed in sensory neurons of the dorsal root and trigeminal ganglia. TRPV1 is a …

TRPV1, a cation channel on sensory nerves sensitive to heat and capsaicin, plays an
important role in the transduction of noxious stimuli to the spinal cord. It is expressed by …

As the world's population ages, the treatment of osteoporosis is a major problem to be
addressed. The cause of osteoporosis remains unclear. Ca 2+ is not only an important …

Transient receptor potential ankyrin 1 (TRPA1) is a membrane-bound ion channel found in
neurons, where it mediates nociception and neurogenic inflammation. Recently, we have …