Adaptation to air breathing at birth is dependent on formation and function of the lung. Lung
morphogenesis is a complex process dependent on precise temporal–spatial control of cell …

Survival at birth depends on the adequate development and maturation of the lung in utero.
Disorders of lung growth, maturation and control of breathing continues to be some of the …

At birth, the successful transition to extra-uterine life is dependent upon the ability of the lung
to take over the role of respiratory gas-exchange. Before birth, the future airways of the lungs …

Bronchopulmonary dysplasia (BPD) is a multi-factorial disease that results from a
combination of clinical factors, including lung immaturity, mechanical ventilation, oxidative …

The unique architecture of the mammalian lung is required for adaptation to air breathing at
birth and thereafter. Understanding the cellular and molecular mechanisms controlling its …

Bronchopulmonary dysplasia (BPD), first described by Northway in 1967, is a process of
neonatal lung injury that is most strongly associated with prematurity. The “old” form of the …

There have been many efforts to develop good animal models of bronchopulmonary
dysplasia (BPD) to better understand the pathophysiology and mechanisms underlying …

Pulmonary inflammation has a central role in the multifactorial and complex pathogenesis of
bronchopulmonary dysplasia. Pre-and postnatal factors such as chorioamnionitis, oxygen …

The lungs serve the primary function of air-blood gas exchange in all mammals and in
terrestrial vertebrates. Efficient gas exchange requires a large surface area that provides …

Introduction 3. Lung Formation 3.1. Embryology 3.2. Development and Structure 3.3. Signal
Transduction Pathways 3.3. 1. RA and Nuclear Receptor Superfamily 3.3. 2. TGFbeta …