The understanding of load support mechanisms in cartilage has evolved with computational
models that better mimic the tissue ultrastructure. Fibril-reinforced poroelastic models can …

The depth dependence of the material properties is present in normal adult cartilage and is
believed to have significant implications in its normal mechanical function. Cartilage …

The strain and strain-rate-dependent response of articular cartilage in unconfined
compression was studied theoretically. The transient stress and stiffness of cartilage were …

From a mechanical point of view, the most relevant components of articular cartilage are the
tight and highly organized collagen network together with the charged proteoglycans. Due to …

The mechanisms underlying the ability of articular cartilage to withstand and distribute the
loads applied across diarthrodial joints have been widely studied. Experimental tests have …

Articular cartilage is the translucent, heterogeneous three-component biological load
processing gel that overlays the end of the articulating bones of mammalian joints. Normally …

The highly inhomogeneous distribution of collagen fibrils may have important effects on the
biphasic mechanics of articular cartilage. However, the effect of the inhomogeneity of …

The growth, maintenance and ossification of cartilage are fundamental to skeletal
development and are regulated throughout life by the mechanical cues that are imposed by …

Cartilage mechanical function relies on a composite structure of a collagen fibrillar network
entrapping a proteoglycan matrix. Previous biphasic or poroelastic models of this tissue …

Articular cartilage tissue exhibits a spatial dependence in material properties that govern
mechanical behaviour. A mathematical model of cartilage tissue under one dimensional …