Targeting methicillin-resistant Staphylococcus aureus with short salt-resistant synthetic peptides
The seriousness of microbial resistance combined with the lack of new antimicrobials has
increased interest in the development of antimicrobial peptides (AMPs) as novel …
increased interest in the development of antimicrobial peptides (AMPs) as novel …
[HTML][HTML] Evaluation of short synthetic antimicrobial peptides for treatment of drug-resistant and intracellular Staphylococcus aureus
Methicillin-resistant Staphylococcus aureus (MRSA) infections present a serious challenge
because of the emergence of resistance to numerous conventional antibiotics. Due to their …
because of the emergence of resistance to numerous conventional antibiotics. Due to their …
Two optimized antimicrobial peptides with therapeutic potential for clinical antibiotic-resistant Staphylococcus aureus
The rapid increase of Methicillin-resistant Staphylococcus aureus (MRSA) infections and the
cross-resistance of MRSA to other antibiotics create an urgent demand for new therapeutic …
cross-resistance of MRSA to other antibiotics create an urgent demand for new therapeutic …
Development of aromatic-linked diamino acid antimicrobial peptide mimics with low hemolytic toxicity and excellent activity against methicillin-resistant …
H Kong, S Qin, D Yan, B Shen, T Zhang… - Journal of Medicinal …, 2023 - ACS Publications
Infections caused by methicillin-resistant Staphylococcus aureus (MRSA) have become one
of the biggest threats to public health. To develop new antibacterial agents against MRSA, a …
of the biggest threats to public health. To develop new antibacterial agents against MRSA, a …
[HTML][HTML] Antimicrobial Peptides with Antibacterial Activity against Vancomycin-Resistant Staphylococcus aureus Strains: Classification, Structures, and Mechanisms of …
I Hernández-Aristizábal, ID Ocampo-Ibáñez - International journal of …, 2021 - mdpi.com
The emergence of bacteria resistant to conventional antibiotics is of great concern in modern
medicine because it renders ineffectiveness of the current empirical antibiotic therapies …
medicine because it renders ineffectiveness of the current empirical antibiotic therapies …
[HTML][HTML] Amphipathic peptide antibiotics with potent activity against multidrug-resistant pathogens
J Shi, C Chen, D Wang, Z Tong, Z Wang, Y Liu - Pharmaceutics, 2021 - mdpi.com
The emergence and prevalence of multidrug-resistant (MDR) bacteria have posed a serious
threat to public health. Of particular concern are methicillin-resistant Staphylococcus aureus …
threat to public health. Of particular concern are methicillin-resistant Staphylococcus aureus …
Database screening and in vivo efficacy of antimicrobial peptides against methicillin-resistant Staphylococcus aureus USA300
Natural antimicrobial peptides (AMPs) are promising candidates for developing a generation
of new antimicrobials to meet the challenge of antibiotic-resistant pathogens such as …
of new antimicrobials to meet the challenge of antibiotic-resistant pathogens such as …
Non hemolytic short peptidomimetics as a new class of potent and broad-spectrum antimicrobial agents
RN Murugan, B Jacob, EH Kim, M Ahn, H Sohn… - Bioorganic & medicinal …, 2013 - Elsevier
Since the bacterial resistance to antibiotics is increasing rapidly, numerous studies have
contributed to the design and synthesis of potent synthetic mimics of antimicrobial peptides …
contributed to the design and synthesis of potent synthetic mimics of antimicrobial peptides …
[HTML][HTML] Hybrid Antimicrobial Peptide Targeting Staphylococcus aureus and Displaying Anti-infective Activity in a Murine Model
L Shang, J Li, C Song, Z Nina, Q Li, S Chou… - Frontiers in …, 2020 - frontiersin.org
Broad-spectrum antimicrobial peptides (AMPs) kill bacteria indiscriminately, increasing the
possibility of an ecological imbalance in the microbiota. To solve this problem, new types of …
possibility of an ecological imbalance in the microbiota. To solve this problem, new types of …
Poly-lysine peptidomimetics having potent antimicrobial activity without hemolytic activity
M Ahn, B Jacob, P Gunasekaran, RN Murugan, EK Ryu… - Amino acids, 2014 - Springer
Diversity of sequence and structure in naturally occurring antimicrobial peptides (AMPs)
limits their intensive structure–activity relationship (SAR) study. In contrast, peptidomimetics …
limits their intensive structure–activity relationship (SAR) study. In contrast, peptidomimetics …