Epidermal growth factor receptor mutation detection using high-resolution melting analysis predicts outcomes in patients with advanced non–small cell lung cancer …
T Takano, Y Ohe, K Tsuta, T Fukui, H Sakamoto… - Clinical cancer …, 2007 - AACR
Purpose: Epidermal growth factor receptor (EGFR) mutations, especially deletional
mutations in exon 19 (DEL) and L858R, predict gefitinib sensitivity in patients with non …
mutations in exon 19 (DEL) and L858R, predict gefitinib sensitivity in patients with non …
Epidermal growth factor receptor mutations in needle biopsy/aspiration samples predict response to gefitinib therapy and survival of patients with advanced nonsmall …
Recently, mutations in the epidermal growth factor receptor (EGFR) gene in nonsmall cell
lung cancer (NSCLC) patients were reported to correlate with gefitinib response. Less than …
lung cancer (NSCLC) patients were reported to correlate with gefitinib response. Less than …
Predictors of gefitinib outcomes in advanced non-small cell lung cancer (NSCLC): study of a comprehensive panel of molecular markers
M Tiseo, G Rossi, M Capelletti, G Sartori, E Spiritelli… - Lung cancer, 2010 - Elsevier
A number of different clinical characteristics and molecular markers related to epidermal
growth factor receptor (EGFR) activation have been reported to singly correlate with …
growth factor receptor (EGFR) activation have been reported to singly correlate with …
Differential effects of gefitinib and cetuximab on non–small-cell lung cancers bearing epidermal growth factor receptor mutations
T Mukohara, JA Engelman, NH Hanna… - Journal of the …, 2005 - academic.oup.com
Background: Many patients with non–small-cell lung cancer (NSCLC) who achieve
radiographic responses to treatment with the epidermal growth factor receptor (EGFR) …
radiographic responses to treatment with the epidermal growth factor receptor (EGFR) …
High frequency of epidermal growth factor receptor mutations with complex patterns in non–small cell lung cancers related to gefitinib responsiveness in Taiwan
SF Huang, HP Liu, LH Li, YC Ku, YN Fu, HY Tsai… - Clinical Cancer …, 2004 - AACR
Purpose: Epidermal growth factor receptor (EGFR) mutations related to gefitinib
responsiveness in non–small cell lung cancer have been found recently. Detection of EGFR …
responsiveness in non–small cell lung cancer have been found recently. Detection of EGFR …
Efficacy of gefitinib for non‐adenocarcinoma non‐small‐cell lung cancer patients harboring epidermal growth factor receptor mutations: A pooled analysis of …
T Shukuya, T Takahashi, R Kaira, A Ono… - Cancer …, 2011 - Wiley Online Library
The efficacy of gefitinib for patients with non‐adenocarcinoma non‐small‐cell lung cancer
(NSCLC) harboring epidermal growth factor receptor (EGFR) mutations is unclear, because …
(NSCLC) harboring epidermal growth factor receptor (EGFR) mutations is unclear, because …
Chemotherapy-induced epidermal growth factor receptor activation determines response to combined gefitinib/chemotherapy treatment in non–small cell lung cancer …
S Van Schaeybroeck, J Kyula, DM Kelly… - Molecular cancer …, 2006 - AACR
Activating epidermal growth factor receptor (EGFR) mutations have been linked with
sensitivity to gefitinib and erlotinib; however, there are no established predictive markers for …
sensitivity to gefitinib and erlotinib; however, there are no established predictive markers for …
Epidermal growth factor receptor messenger RNA expression, gene dosage, and gefitinib sensitivity in non–small cell lung cancer
R Dziadziuszko, SE Witta, F Cappuzzo, S Park… - Clinical Cancer …, 2006 - AACR
Purpose: Epidermal growth factor receptor (EGFR) mRNA expression and EGFR gene
dosage by quantitative PCR in tumor samples obtained from patients with gefitinib-treated …
dosage by quantitative PCR in tumor samples obtained from patients with gefitinib-treated …
[HTML][HTML] Epidermal growth factor receptor mutations and their correlation with gefitinib therapy in patients with non-small cell lung cancer: a meta-analysis based on …
YL Wu, WZ Zhong, LY Li, XT Zhang, L Zhang… - Journal of Thoracic …, 2007 - Elsevier
Background Convincing data on epidermal growth factor receptor (EGFR) mutations in
Chinese patients with non-small-cell lung cancer (NSCLC) remain limited. We investigated …
Chinese patients with non-small-cell lung cancer (NSCLC) remain limited. We investigated …
EGFR genetic heterogeneity of nonsmall cell lung cancers contributing to acquired gefitinib resistance
SX Jiang, K Yamashita, M Yamamoto… - … journal of cancer, 2008 - Wiley Online Library
Gefitinib is dramatically effective for nonsmall cell lung cancers (NSCLCs) with activating
mutations of the epidermal growth factor receptor (EGFR) gene, but these tumors eventually …
mutations of the epidermal growth factor receptor (EGFR) gene, but these tumors eventually …