Levosimendan in paediatric cardiac anaesthesiology: A systematic review and meta-analysis

M Lapere, F Rega, S Rex - European Journal of Anaesthesiology …, 2022 - journals.lww.com
BACKGROUND Low cardiac output syndrome (LCOS) after congenital cardiac surgery has
an incidence of up to 25%. Preventing and treating LCOS is of pivotal importance as LCOS …

Prophylactic use of levosimendan in preoperative setting for surgical repair of congenital heart disease in children

L Wannaz, L Boillat, MH Perez, S Di Bernardo - Frontiers in Pediatrics, 2023 - frontiersin.org
Introduction Low cardiac output syndrome (LCOS) is a significant cause of morbidity and the
leading cause of mortality after pediatric cardiac surgery. Levosimendan has been shown …

Effect of levosimendan treatment in pediatric patients with cardiac dysfunction: an update of a systematic review and meta-analysis of randomized controlled trials

S Silvetti, A Belletti, S Bianzina, M Momeni - Journal of cardiothoracic and …, 2022 - Elsevier
Levosimendan increasingly has been used to treat heart failure and cardiac dysfunction in
pediatric patients. Currently, there is only limited evidence that this drug positively affects …

Clinical efficacy of levosimendan vs milrinone in preventing low cardiac output syndrome following pediatric cardiac surgery

K Jothinath, S Balakrishnan, V Raju… - Annals of Cardiac …, 2021 - journals.lww.com
Background: Prophylactic milrinone is commonly used to prevent Low Cardiac Output
Syndrome (LCOS) after pediatric cardiac surgery. This study compares the use of …

Prophylactic levosimendan for the prevention of low cardiac output syndrome and mortality in paediatric patients undergoing surgery for congenital heart disease

J Hummel, G Ruecker, B Stiller - Cochrane Database of …, 2017 - cochranelibrary.com
Background Low cardiac output syndrome remains a serious complication, and accounts for
substantial morbidity and mortality in the postoperative course of paediatric patients …

Effect of prophylactic levosimendan on all-cause mortality in pediatric patients undergoing cardiac surgery—an updated systematic review and meta-analysis

H Wang, Q Luo, Y Li, L Zhang, X Wu, F Yan - Frontiers in Pediatrics, 2020 - frontiersin.org
Background: Levosimendan, a calcium sensitizer, enhances the myocardial function by
generating more energy-efficient myocardial contractility than that achieved through …

Levosimendan infusion in newborns after corrective surgery for congenital heart disease: randomized controlled trial

Z Ricci, C Garisto, I Favia, V Vitale, L Di Chiara… - Intensive care …, 2012 - Springer
Purpose To evaluate the safety and efficacy of levosimendan in neonates with congenital
heart disease undergoing cardiac surgery with cardiopulmonary bypass (CPB). Methods …

[引用][C] First experience with levosimendan therapy after correction of congenital heart disease

R Giordano, M Cantinotti, VA Mannacio… - … of Cardiothoracic and …, 2017 - jcvaonline.com
Low-Cardiac-Output Syndrome (LCOS) early after cardiopulmonary bypass (CPB) is a well-
known problem in the postoperative course after complex congenital heart surgery, which …

Use of levosimendan in postoperative setting after surgical repair of congenital heart disease in children

V Amiet, MH Perez, D Longchamp, T Boulos Ksontini… - Pediatric …, 2018 - Springer
Low cardiac output is one of the most common complications after cardiac surgery.
Levosimendan, a new inotrope agent, has been demonstrated in adult patient to be an …

Retrospective descriptive study about the use of levosimendan in children undergoing surgical correction for congenital heart disease

F de Palencia-Espinosa… - Revista Española de …, 2012 - europepmc.org
[Retrospective descriptive study about the use of levosimendan in children undergoing surgical
correction for congenital heart disease]. - Abstract - Europe PMC Sign in | Create an account …