Oxidative stress, caused by excessive production of reactive oxygen species (ROS), plays a
crucial role in the occurrence and development of ulcerative colitis (UC). We developed …

Disruption of intestinal homeostasis is an important event in the development of
inflammatory bowel disease (IBD), and genistein (GEN) is a candidate medicine to prevent …

Nanoparticles (NPs) have the capacity to improve the bioactivity and bioavailability of anti-
inflammatory drugs. Here, a green drug nanocarrier based on ovalbumin (OVA) was facilely …

Ulcerative colitis (UC) is a chronic or relapsing inflammatory disease with limited therapeutic
outcomes. Pterostilbene (PSB) is a polyphenol-based anti-oxidant that has received …

Dysfunction of the intestinal mucosal immune system and dysbiosis of the intestinal
microflora can induce inflammatory bowel disease. However, drug-mediated clinical …

Herein, dual-bioresponsive of Rhein (RH) in promoting colonic mucous damage repair and
controlling inflammatory reactions were combined by the dual-targeting (intestinal epithelial …

Ulcerative colitis (UC) is a chronic inflammatory illness affecting the colon and rectum, with
current treatment methods being unable to meet the clinical needs of ulcerative colitis …

Orally targeted strategy of anti-inflammatory agents has attracted tremendous attention for
reducing highly health-care costs and enhancing the intervention efficiency of ulcerative …

Oxidative stress is a key factor in the development of inflammatory diseases. Elimination of
reactive oxygen species (ROS) in the inflamed colon has been confirmed as an effective …

The therapeutic efficacies of oral nanotherapeutics for ulcerative colitis (UC) are seriously
hindered by the lack of mucus-penetrating capacity and uncontrolled drug release. To …