Nanozyme enabled protective therapy for neurological diseases

F Cheng, S Kotha, M Fu, Q Yang, H Wang, W He… - Nano Today, 2024 - Elsevier
Nanozymes are nanomaterials that mimic enzymatic activities found in natural human
biological processes. Nanozymes can perform reactive oxidative species (ROS) scavenging …

Nanozyme-based strategies for efficient theranostics of brain diseases

R Xu, S Zhang, P Wang, R Zhang, P Lin, Y Wang… - Coordination Chemistry …, 2024 - Elsevier
Oxidative stress emerges as a critical mechanism underlying the development and
progression of various brain diseases, arising from either increased generation of reactive …

[HTML][HTML] The applications of nanozymes in neurological diseases: from mechanism to design

Y Zhang, L Zhang, M Wang, P Li - Theranostics, 2023 - ncbi.nlm.nih.gov
Nanozymes are a class of nanomaterials with enzyme-like catalytic activities. Due to their
multiple catalytic activities, as well as their good stability, modifiable activity and other …

Nanozymes regulate redox homeostasis in ROS-related inflammation

Q Li, Y Liu, X Dai, W Jiang, H Zhao - Frontiers in Chemistry, 2021 - frontiersin.org
Reactive oxygen species (ROS), in moderate amounts, play an essential role in regulating
different physiological functions in organisms. However, increased amounts of ROS may …

Nanozyme-based medicine for enzymatic therapy: progress and challenges

Q Wang, J Jiang, L Gao - Biomedical Materials, 2021 - iopscience.iop.org
Nanozymes are nanomaterials with enzyme-like characteristics. As a new generation of
artificial enzymes, nanozymes have the advantages of low cost, good stability, simple …

Nanozyme antioxidants as emerging alternatives for natural antioxidants: Achievements and challenges in perspective

M Ghorbani, H Derakhshankhah, S Jafari, S Salatin… - Nano Today, 2019 - Elsevier
Nanozymes are nanoparticulated structures with the inherent enzymatic activities, which
their advances in bio/nanomedicine field are progressively growing regarding their …

Catalytic nanozymes for central nervous system disease

K Chen, S Sun, J Wang, XD Zhang - Coordination Chemistry Reviews, 2021 - Elsevier
The central nervous system (CNS) is a centralized control system for the human body, and
minor lesions or injuries will cause inestimable consequences. Due to high oxygen …

Bioactive material-based nanozymes with multifunctional attributes for biomedicine: expanding antioxidant therapeutics for neuroprotection, cancer, and anti …

DO Lopez-Cantu, RB González-González… - Coordination Chemistry …, 2022 - Elsevier
Considering the biochemical rationale, the deployments of enzymes as therapeutic targets
against several oxidative stress-related diseases have been hindered by the limitations of …

Recent advancements in the formulation of nanomaterials-based nanozymes, their catalytic activity, and biomedical applications

S Singh, N Rai, H Tiwari, P Gupta, A Verma… - ACS Applied Bio …, 2023 - ACS Publications
Nanozymes are nanoparticles with intrinsic enzyme-mimicking properties that have become
more prevalent because of their ability to outperform conventional enzymes by overcoming …

Therapy of mitochondria-targeted hybrid nanozymes for reactive oxygen species-induced diseases

Z Wang, Z Shen, S Lin, X Mei - Applied Materials Today, 2023 - Elsevier
The development of enzyme mimetics that clear excess mitochondrial reactive oxidative
stress (ROS) could provide effective treatment for a wide variety of diseases. Herein …