Ultra-hypofractionated versus conventionally fractionated radiotherapy for prostate cancer: 5-year outcomes of the HYPO-RT-PC randomised, non-inferiority, phase 3 …
A Widmark, A Gunnlaugsson, L Beckman… - The Lancet, 2019 - thelancet.com
Background Hypofractionated radiotherapy for prostate cancer has gained increased
attention due to its proposed high radiation-fraction sensitivity. Recent reports from studies …
attention due to its proposed high radiation-fraction sensitivity. Recent reports from studies …
Ultra-hypofractionated versus conventionally fractionated radiotherapy for prostate cancer (HYPO-RT-PC): patient-reported quality-of-life outcomes of a randomised …
P Fransson, P Nilsson, A Gunnlaugsson… - The Lancet …, 2021 - thelancet.com
Summary Background The HYPO-RT-PC trial compared conventionally fractionated
radiotherapy with ultra-hypofractionated radiotherapy in patients with localised prostate …
radiotherapy with ultra-hypofractionated radiotherapy in patients with localised prostate …
Hypofractionated versus conventionally fractionated radiotherapy for patients with prostate cancer (HYPRO): late toxicity results from a randomised, non-inferiority …
S Aluwini, F Pos, E Schimmel, S Krol… - The Lancet …, 2016 - thelancet.com
Background Several studies have reported a low α to β ratio for prostate cancer, suggesting
that hypofractionation could enhance the biological tumour dose without increasing …
that hypofractionation could enhance the biological tumour dose without increasing …
Hypofractionated versus conventionally fractionated radiotherapy for patients with prostate cancer (HYPRO): acute toxicity results from a randomised non-inferiority …
S Aluwini, F Pos, E Schimmel, E van Lin, S Krol… - The Lancet …, 2015 - thelancet.com
Background In 2007, we began the randomised phase 3 multicentre HYPRO trial to
investigate the effect of hypofractionated radiotherapy compared with conventionally …
investigate the effect of hypofractionated radiotherapy compared with conventionally …
Hypofractionated versus conventionally fractionated radiotherapy for patients with localised prostate cancer (HYPRO): final efficacy results from a randomised …
L Incrocci, RC Wortel, WG Alemayehu… - The Lancet …, 2016 - thelancet.com
Background Studies have reported a low α/β ratio for prostate cancer, suggesting that
hypofractionation could enhance the biological tumour dose without increasing …
hypofractionation could enhance the biological tumour dose without increasing …
Systematic review of hypofractionated radiation therapy for prostate cancer
Prostate cancer is the second most prevalent solid tumor diagnosed in men in the United
States and Western Europe. Conventionally fractionated external beam radiation therapy …
States and Western Europe. Conventionally fractionated external beam radiation therapy …
A systematic review of hypofractionation for primary management of prostate cancer
BF Koontz, A Bossi, C Cozzarini, T Wiegel, A D'Amico - European urology, 2015 - Elsevier
Context Technological advances in radiation therapy delivery have permitted the use of high-
dose-per-fraction radiation therapy (RT) for early-stage prostate cancer (PCa). Level 1 …
dose-per-fraction radiation therapy (RT) for early-stage prostate cancer (PCa). Level 1 …
Ultrahypofractionated versus hypofractionated and conventionally fractionated radiation therapy for localized prostate cancer: A systematic review and meta-analysis …
Introduction To characterize the efficacy (5-year disease-free survival [DFS]) and safety
(incidence of grade 2+ late gastrointestinal or genitourinary toxicity) of ultrahypofractionated …
(incidence of grade 2+ late gastrointestinal or genitourinary toxicity) of ultrahypofractionated …
Diminishing returns from ultrahypofractionated radiation therapy for prostate cancer
IR Vogelius, SM Bentzen - … Journal of Radiation Oncology* Biology* Physics, 2020 - Elsevier
Purpose More than a decade of randomized controlled trials in prostate cancer has
established a positive radiation dose response at moderate doses and a consistently low α/β …
established a positive radiation dose response at moderate doses and a consistently low α/β …
Conventional versus hypofractionated high-dose intensity-modulated radiotherapy for prostate cancer: 5-year outcomes of the randomised, non-inferiority, phase 3 …
D Dearnaley, I Syndikus, H Mossop, V Khoo… - The Lancet …, 2016 - thelancet.com
Background Prostate cancer might have high radiation-fraction sensitivity that would give a
therapeutic advantage to hypofractionated treatment. We present a pre-planned analysis of …
therapeutic advantage to hypofractionated treatment. We present a pre-planned analysis of …
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