Helper T-cell antigenic site identification in the acquired immunodeficiency syndrome virus gp120 envelope protein and induction of immunity in mice to the native …
KB Cease, H Margalit, JL Cornette… - Proceedings of the …, 1987 - National Acad Sciences
Much effort has been devoted to the analysis of antibodies to acquired immunodeficiency
syndrome virus antigens, but no studies, to our knowledge, have defined antigenic sites of …
syndrome virus antigens, but no studies, to our knowledge, have defined antigenic sites of …
Polyvalent human immunodeficiency virus synthetic immunogen comprised of envelope gp120 T helper cell sites and B cell neutralization epitopes.
TJ Palker, TJ Matthews, A Langlois… - … (Baltimore, Md.: 1950 …, 1989 - journals.aai.org
In previous studies, we have used antisera raised to envelope (env)-gene-encoded
synthetic peptides to identify a region of (HIV) glycoprotein (gp) 120 env protein designated …
synthetic peptides to identify a region of (HIV) glycoprotein (gp) 120 env protein designated …
The naive repertoire of human T helper cells specific for gp120, the envelope glycoprotein of HIV.
F Manca, J Habeshaw, A Dalgleish - Journal of immunology …, 1991 - journals.aai.org
The envelope glycoprotein of HIV gp120 is a T cell Ag in experimental animals and in
humans infected with HIV or deliberately immunized with gp120 in various forms. Inasmuch …
humans infected with HIV or deliberately immunized with gp120 in various forms. Inasmuch …
Type-specific neutralization of the human immunodeficiency virus with antibodies to env-encoded synthetic peptides.
TJ Palker, ME Clark, AJ Langlois… - Proceedings of the …, 1988 - National Acad Sciences
A synthetic peptide (SP-10-IIIB) with an amino acid sequence [Cys-Thr-Arg-Pro-Asn-Asn-
Asn-Thr-Arg-Lys-Ser-Ile-Arg-Ile-Gln-Arg-Gly-Pro-Pro-Gly-(Tyr); amino acids 303-321] from …
Asn-Thr-Arg-Lys-Ser-Ile-Arg-Ile-Gln-Arg-Gly-Pro-Pro-Gly-(Tyr); amino acids 303-321] from …
Synthetic peptides containing T and B cell epitopes from human immunodeficiency virus envelope gp120 induce anti-HIV proliferative responses and high titers of …
MK Hart, TJ Palker, TJ Matthews… - … (Baltimore, Md.: 1950 …, 1990 - journals.aai.org
We have previously described a synthetic peptide (T1-SP10) derived from two
noncontiguous regions of HTLVIIIB envelope gp120 (T1, amino acids 428-443; SP10, amino …
noncontiguous regions of HTLVIIIB envelope gp120 (T1, amino acids 428-443; SP10, amino …
Priming of CD4+ T cells specific for conserved regions of human immunodeficiency virus glycoprotein gp120 in humans immunized with a recombinant envelope …
S Abrignani, D Montagna, M Jeannet… - Proceedings of the …, 1990 - National Acad Sciences
A nonglycosylated denatured form of human immunodeficiency virus (HIV) 1 glycoprotein
gp120 (Env 2-3), which does not bind to CD4, was used with muramyl tripeptide as adjuvant …
gp120 (Env 2-3), which does not bind to CD4, was used with muramyl tripeptide as adjuvant …
Construction of peptides encompassing multideterminant clusters of human immunodeficiency virus envelope to induce in vitro T cell responses in mice and humans …
JA Berzofsky, CD Pendleton, M Clerici… - The Journal of …, 1991 - Am Soc Clin Investig
To make synthetic peptide vaccines effective in a broad population of outbred humans, one
would have to incorporate enough antigenic determinants to elicit recognition by T cells of …
would have to incorporate enough antigenic determinants to elicit recognition by T cells of …
Induction of anti‐HIV neutralizing antibodies by synthetic peptides.
TC Chanh, GR Dreesman, P Kanda, GP Linette… - The EMBO …, 1986 - embopress.org
Two synthetic peptides containing amino acid sequences analogous to the envelope
glycoprotein of human T‐lymphotropic virus (HTLV) type III (HTLV‐III) and lymphadenopathy …
glycoprotein of human T‐lymphotropic virus (HTLV) type III (HTLV‐III) and lymphadenopathy …
Identification of human neutralization-inducing regions of the human immunodeficiency virus type 1 envelope glycoproteins.
PA Broliden, A von Gegerfelt… - Proceedings of the …, 1992 - National Acad Sciences
Four major neutralizing regions of the human immunodeficiency virus type 1 (HIV-1)
envelope glycoprotein were identified and characterized with a panel of 80 HIV-1 antibody …
envelope glycoprotein were identified and characterized with a panel of 80 HIV-1 antibody …
Prospect for prevention of human immunodeficiency virus infection: purified 120-kDa envelope glycoprotein induces neutralizing antibody.
WG Robey, LO Arthur, TJ Matthews… - Proceedings of the …, 1986 - National Acad Sciences
This study initiates an effort to develop a safe vaccine against the acquired
immunodeficiency syndrome (AIDS) that is caused by infection with a retrovirus designated …
immunodeficiency syndrome (AIDS) that is caused by infection with a retrovirus designated …
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