Type-specific neutralization of the human immunodeficiency virus with antibodies to env-encoded synthetic peptides.
TJ Palker, ME Clark, AJ Langlois… - Proceedings of the …, 1988 - National Acad Sciences
A synthetic peptide (SP-10-IIIB) with an amino acid sequence [Cys-Thr-Arg-Pro-Asn-Asn-
Asn-Thr-Arg-Lys-Ser-Ile-Arg-Ile-Gln-Arg-Gly-Pro-Pro-Gly-(Tyr); amino acids 303-321] from …
Asn-Thr-Arg-Lys-Ser-Ile-Arg-Ile-Gln-Arg-Gly-Pro-Pro-Gly-(Tyr); amino acids 303-321] from …
Polyvalent human immunodeficiency virus synthetic immunogen comprised of envelope gp120 T helper cell sites and B cell neutralization epitopes.
TJ Palker, TJ Matthews, A Langlois… - … (Baltimore, Md.: 1950 …, 1989 - journals.aai.org
In previous studies, we have used antisera raised to envelope (env)-gene-encoded
synthetic peptides to identify a region of (HIV) glycoprotein (gp) 120 env protein designated …
synthetic peptides to identify a region of (HIV) glycoprotein (gp) 120 env protein designated …
Induction of anti‐HIV neutralizing antibodies by synthetic peptides.
TC Chanh, GR Dreesman, P Kanda, GP Linette… - The EMBO …, 1986 - embopress.org
Two synthetic peptides containing amino acid sequences analogous to the envelope
glycoprotein of human T‐lymphotropic virus (HTLV) type III (HTLV‐III) and lymphadenopathy …
glycoprotein of human T‐lymphotropic virus (HTLV) type III (HTLV‐III) and lymphadenopathy …
Synthetic peptides containing T and B cell epitopes from human immunodeficiency virus envelope gp120 induce anti-HIV proliferative responses and high titers of …
MK Hart, TJ Palker, TJ Matthews… - … (Baltimore, Md.: 1950 …, 1990 - journals.aai.org
We have previously described a synthetic peptide (T1-SP10) derived from two
noncontiguous regions of HTLVIIIB envelope gp120 (T1, amino acids 428-443; SP10, amino …
noncontiguous regions of HTLVIIIB envelope gp120 (T1, amino acids 428-443; SP10, amino …
Helper T-cell antigenic site identification in the acquired immunodeficiency syndrome virus gp120 envelope protein and induction of immunity in mice to the native …
KB Cease, H Margalit, JL Cornette… - Proceedings of the …, 1987 - National Acad Sciences
Much effort has been devoted to the analysis of antibodies to acquired immunodeficiency
syndrome virus antigens, but no studies, to our knowledge, have defined antigenic sites of …
syndrome virus antigens, but no studies, to our knowledge, have defined antigenic sites of …
Identification of human neutralization-inducing regions of the human immunodeficiency virus type 1 envelope glycoproteins.
PA Broliden, A von Gegerfelt… - Proceedings of the …, 1992 - National Acad Sciences
Four major neutralizing regions of the human immunodeficiency virus type 1 (HIV-1)
envelope glycoprotein were identified and characterized with a panel of 80 HIV-1 antibody …
envelope glycoprotein were identified and characterized with a panel of 80 HIV-1 antibody …
Epitopes recognized by the neutralizing antibodies of an HIV-1-infected individual.
AT Profy, PA Salinas, LI Eckler, NM Dunlop… - … (Baltimore, Md.: 1950 …, 1990 - journals.aai.org
Sera from individuals infected by HIV-1 usually neutralize multiple viral isolates. To
determine the extent to which these neutralizing antibodies recognize a principal …
determine the extent to which these neutralizing antibodies recognize a principal …
Human immunodeficiency virus type 1 neutralization epitope with conserved architecture elicits early type-specific antibodies in experimentally infected chimpanzees.
J Goudsmit, C Debouck, RH Meloen… - Proceedings of the …, 1988 - National Acad Sciences
Chimpanzees are susceptible to infection by divergent strains of human immunodeficiency
virus type 1 (HIV-1), none of which cause clinical or immunological abnormalities …
virus type 1 (HIV-1), none of which cause clinical or immunological abnormalities …
Purified envelope glycoproteins from human immunodeficiency virus type 1 variants induce individual, type-specific neutralizing antibodies
Repeated immunizations of goats, horses, or chimpanzees with envelope glycoprotein
gp120 isolated from human immunodeficiency virus type 1 (HIV-1) resulted in type-specific …
gp120 isolated from human immunodeficiency virus type 1 (HIV-1) resulted in type-specific …
Broadly neutralizing antibodies elicited by the hypervariable neutralizing determinant of HIV-1
K Javaherian, AJ Langlois, GJ LaRosa, AT Profy… - Science, 1990 - science.org
The principal neutralizing determinant (PND) of human immunodeficiency virus (HIV)-1
resides within the V3 loop of the envelope protein. Antibodies elicited by peptides of this …
resides within the V3 loop of the envelope protein. Antibodies elicited by peptides of this …