Polyvalent human immunodeficiency virus synthetic immunogen comprised of envelope gp120 T helper cell sites and B cell neutralization epitopes.
TJ Palker, TJ Matthews, A Langlois… - … (Baltimore, Md.: 1950 …, 1989 - journals.aai.org
In previous studies, we have used antisera raised to envelope (env)-gene-encoded
synthetic peptides to identify a region of (HIV) glycoprotein (gp) 120 env protein designated …
synthetic peptides to identify a region of (HIV) glycoprotein (gp) 120 env protein designated …
Synthetic peptides containing T and B cell epitopes from human immunodeficiency virus envelope gp120 induce anti-HIV proliferative responses and high titers of …
MK Hart, TJ Palker, TJ Matthews… - … (Baltimore, Md.: 1950 …, 1990 - journals.aai.org
We have previously described a synthetic peptide (T1-SP10) derived from two
noncontiguous regions of HTLVIIIB envelope gp120 (T1, amino acids 428-443; SP10, amino …
noncontiguous regions of HTLVIIIB envelope gp120 (T1, amino acids 428-443; SP10, amino …
Type-specific neutralization of the human immunodeficiency virus with antibodies to env-encoded synthetic peptides.
TJ Palker, ME Clark, AJ Langlois… - Proceedings of the …, 1988 - National Acad Sciences
A synthetic peptide (SP-10-IIIB) with an amino acid sequence [Cys-Thr-Arg-Pro-Asn-Asn-
Asn-Thr-Arg-Lys-Ser-Ile-Arg-Ile-Gln-Arg-Gly-Pro-Pro-Gly-(Tyr); amino acids 303-321] from …
Asn-Thr-Arg-Lys-Ser-Ile-Arg-Ile-Gln-Arg-Gly-Pro-Pro-Gly-(Tyr); amino acids 303-321] from …
Helper T-cell antigenic site identification in the acquired immunodeficiency syndrome virus gp120 envelope protein and induction of immunity in mice to the native …
KB Cease, H Margalit, JL Cornette… - Proceedings of the …, 1987 - National Acad Sciences
Much effort has been devoted to the analysis of antibodies to acquired immunodeficiency
syndrome virus antigens, but no studies, to our knowledge, have defined antigenic sites of …
syndrome virus antigens, but no studies, to our knowledge, have defined antigenic sites of …
Specific cellular immune response and neutralizing antibodies in goats immunized with native or recombinant envelope proteins derived from human T-lymphotropic …
K Krohn, WG Robey, S Putney… - Proceedings of the …, 1987 - National Acad Sciences
Animals immunized with native or recombinant envelope proteins from the human
immunodeficiency virus (HIV, formerly referred to as human T-lymphotropic virus type III) …
immunodeficiency virus (HIV, formerly referred to as human T-lymphotropic virus type III) …
B-and T-lymphocyte responses to an immunodominant epitope of human immunodeficiency virus
RD Schrier, JW Gnann Jr, AJ Langlois… - Journal of …, 1988 - Am Soc Microbiol
Using synthetic peptides, we characterized the B-lymphocyte (antibody) and T-lymphocyte
(proliferation) responses to an immunodominant epitope of human immunodeficiency virus …
(proliferation) responses to an immunodominant epitope of human immunodeficiency virus …
A universal T cell epitope-containing peptide from hepatitis B surface antigen can enhance antibody specific for HIV gp120.
JL Greenstein, VC Schad, WH Goodwin… - … (Baltimore, Md.: 1950 …, 1992 - journals.aai.org
Peptide-based vaccines that directly target T cell or B cell epitopes may have significant
advantages over conventional vaccines. Further, synthetic chimeric peptides that combine …
advantages over conventional vaccines. Further, synthetic chimeric peptides that combine …
Induction of antibodies to the human immunodeficiency virus type 1 by immunization of baboons with immunoglobulin molecules carrying the principal neutralizing …
H Zaghouani, SA Anderson… - Proceedings of the …, 1995 - National Acad Sciences
The hypervariable region 3 (V3) within the disulfide-bridged loop of the envelope protein of
the human immunodeficiency virus type 1 (HIV-1) contains an amino acid sequence that …
the human immunodeficiency virus type 1 (HIV-1) contains an amino acid sequence that …
Confronting the hypervariability of an immunodominant epitope eliciting virus neutralizing antibodies from the envelope glycoprotein of the human immunodeficiency …
AR Neurath, N Strick - Molecular immunology, 1990 - Elsevier
Antibody mediated and cell mediated immune responses to the envelope glycoproteins
gp120 and gp41 of the human immunodeficiency virus (HIV-1) are considered important for …
gp120 and gp41 of the human immunodeficiency virus (HIV-1) are considered important for …
Priming with T helper cell epitope peptides enhances the antibody response to the envelope glycoprotein of HIV-1 in primates.
A Hosmalin, PL Nara, M Zweig, NW Lerche… - … (Baltimore, Md.: 1950 …, 1991 - journals.aai.org
The induction of a memory immune response to HIV, mediated by any kind of effector
mechanism, requires the induction of T cell help. In previous studies performed in different …
mechanism, requires the induction of T cell help. In previous studies performed in different …