Development of dual-drug-loaded stealth nanocarriers for targeted and synergistic anti-lung cancer efficacy

J Chen, X Yang, L Huang, H Lai, C Gan, X Luo - Drug delivery, 2018 - Taylor & Francis
Combination chemotherapy is widely exploited for suppressing drug resistance and
achieving synergistic anticancer efficacy in the clinic. In this paper, the nanostructured …

Aptamer-functionalized albumin-based nanoparticles for targeted drug delivery

L Xu, XY He, BY Liu, C Xu, SL Ai, RX Zhuo… - Colloids and Surfaces B …, 2018 - Elsevier
Proteins have been extensively explored as versatile nanocarriers for drug delivery due to
their complete biocompatibility, ease of surface modification, and lack of toxicity and …

Targeted delivery of cancer drug paclitaxel to chordomas tumor cells via an RNA nanoparticle harboring an EGFR aptamer

D Xiao, Y Huang, S Huang, J Zhuang, P Chen… - Colloids and Surfaces B …, 2022 - Elsevier
Paclitaxel has been extensively used in clinics for cancer treatment. However, its limited
solubility in aqueous solution and high occurrence of side effects have also been widely …

[HTML][HTML] Characterization of cisplatin-loaded chitosan nanoparticles and rituximab-linked surfaces as target-specific injectable nano-formulations for combating cancer

MH Sultan, SS Moni, OA Madkhali, MA Bakkari… - Scientific reports, 2022 - nature.com
The present study was carried out to develop cisplatin-loaded chitosan nanoparticles
(CCNP) and cisplatin-loaded chitosan nanoparticle surface linked to rituximab (mAbCCNP) …

[HTML][HTML] HPA aptamer functionalized paclitaxel-loaded PLGA nanoparticles for enhanced anticancer therapy through targeted effects and microenvironment …

T Duan, Z Xu, F Sun, Y Wang, J Zhang, C Luo… - Biomedicine & …, 2019 - Elsevier
Breast cancer is a fairly common cancer with high mortality in women worldwide. Targeted
nano-drug delivery system for breast cancer treatment has achieved encouraging results …

Chitosan/poly (lactic acid)-coated piceatannol nanoparticles exert an in vitro apoptosis activity on liver, lung and breast cancer cell lines

J Dhanapal… - … cells, nanomedicine, and …, 2018 - Taylor & Francis
The aim of the study was to synthesize nanoparticles (NPs) with chitosan (CS), and poly
(lactic acid)(PLA) as a carrier for the drug piceatannol (PIC). The synthesized nanoparticles …

Folic-acid adorned alginate-polydopamine modified paclitaxel/Zn-CuO nanocomplex for pH triggered drug release and synergistic antitumor efficacy

S Singh, K Pal - International Journal of Biological Macromolecules, 2023 - Elsevier
Targeted chemotherapy is a prominent cancer treatment research trend that intends to boost
the efficacy of drug delivery to cancer cells. The present work aimed to design, a folate …

[HTML][HTML] Unveiling the potentials of biocompatible silver nanoparticles on human lung carcinoma A549 cells and Helicobacter pylori

K Saravanakumar, R Chelliah, D MubarakAli, DH Oh… - Scientific reports, 2019 - nature.com
Silver nanoparticles (AgNPs) are gaining importance in health and environment. This study
synthesized AgNPs using the bark extract of a plant, Toxicodendron vernicifluum (Tv) as …

Exploring paclitaxel-loaded adenosine-conjugated PEGylated PLGA nanoparticles for targeting triple-negative breast cancer

D Chaudhari, K Kuche, V Yadav, R Ghadi… - Drug Delivery and …, 2023 - Springer
In present investigation, we developed paclitaxel (PTX)-loaded adenosine (ADN)-
conjugated PLGA nanoparticles for combating triple-negative breast cancer (TNBC), where …

[HTML][HTML] Cabazitaxel-loaded human serum albumin nanoparticles combined with TGFβ-1 siRNA lipid nanoparticles for the treatment of paclitaxel-resistant non-small …

T Tan, Y Feng, W Wang, R Wang, L Yin, Y Zeng… - Cancer …, 2023 - Springer
Background In the current treatment of non-small cell lung cancer (NSCLC), traditional
chemotherapy causes high toxicity, so it is necessary to develop safe chemical drug delivery …