A dual synergetic nanoreactor for managing parkinson's disease by regulating inflammation and mitigating oxidative damage

Q Li, T Wu, OU Akakuru, N Song, W Liu… - Advanced Functional …, 2023 - Wiley Online Library
Glial cell‐dominated inflammatory microenvironment and neuronal damage due to oxidative
stress are major impediments to the treatment of central nervous degenerative diseases …

Metal–Organic Framework Based Nanozyme System for NLRP3 Inflammasome‐Mediated Neuroinflammatory Regulation in Parkinson's Disease

Q Li, X Ding, Z Chang, X Fan, J Pan… - Advanced …, 2024 - Wiley Online Library
Neuroinflammation is associated with a series of pathological symptoms in Parkinson's
disease (PD), including α‐synuclein aggregation and dopaminergic neuronal death. The …

Chiral metal-organic frameworks incorporating nanozymes as neuroinflammation inhibitors for managing Parkinson's disease

W Jiang, Q Li, R Zhang, J Li, Q Lin, J Li, X Zhou… - Nature …, 2023 - nature.com
Nanomedicine-based anti-neuroinflammation strategy has become a promising dawn of
Parkinson's disease (PD) treatment. However, there are significant gaps in our …

An upconversion nanoplatform based multi-effective theatment for Parkinson's disease

B Hu, H Fang, Z Huang, W Huang, L Huang… - Chemical Engineering …, 2023 - Elsevier
Parkinson's disease (PD) is a complex neurodegenerative disease affected by many factors.
Although there are treatments to combat the symptoms of PD, such as levodopa and deep …

[HTML][HTML] Ultrasmall coordination polymers for alleviating ROS-mediated inflammatory and realizing neuroprotection against Parkinson's disease

G Cheng, X Liu, Y Liu, Y Liu, R Ma, J Luo, X Zhou… - Research, 2022 - spj.science.org
Parkinson's disease (PD) is the second most common neurodegenerative disease globally,
and there is currently no effective treatment for this condition. Excessive accumulation of …

Tri-element nanozyme PtCuSe as an ingenious cascade catalytic machine for the amelioration of Parkinson's disease-like symptoms

H Xu, X Ding, L Li, Q Li, Z Li, H Lin - Frontiers in Bioengineering and …, 2023 - frontiersin.org
Parkinson's disease (PD), as the second most common neurodegenerative disease after
Alzheimer's, has become intractable with the increasing aging global population. The …

Selenium-core nanozymes dynamically regulates Aβ & neuroinflammation circulation: augmenting repair of nervous damage

Y Gong, A Huang, X Guo, Z Jia, X Chen, X Zhu… - Chemical Engineering …, 2021 - Elsevier
The entangled dynamic circulation between β-amyloid (Aβ) and neuroinflammation is the
main reason for the failure of monotherapy in Alzheimer's disease (AD) at present …

Recent advances of nanomaterials for intervention in Parkinson's disease in the context of anti-inflammation

R Zhang, X Chen, Y Cheng, Z Chen, X Li… - Coordination Chemistry …, 2024 - Elsevier
Inflammation and neuroinflammation play critical roles in the pathogenesis of
neurodegenerative diseases such as Parkinson's disease (PD). Nanomaterials with reactive …

A functionalized octahedral palladium nanozyme as a radical scavenger for ameliorating Alzheimer's disease

Z Jia, X Yuan, J Wei, X Guo, Y Gong, J Li… - … Applied Materials & …, 2021 - ACS Publications
Oxidative stress is always mentioned as a pathologic appearance of Alzheimer's disease
(AD). It is attributed to mitochondrial dysfunction closely linked to Aβ deposition and …

Targeting microglia for therapy of Parkinson's disease by using biomimetic ultrasmall nanoparticles

H Liu, Y Han, T Wang, H Zhang, Q Xu… - Journal of the …, 2020 - ACS Publications
Microglia as an important type of innate immune cell in the brain have been considered as
an effective therapeutic target for the treatment of central nervous degenerative diseases …