[HTML][HTML] Functional characteristics of the human ortholog of riboflavin transporter 2 and riboflavin-responsive expression of its rat ortholog in the small intestine indicate …

M Fujimura, S Yamamoto, T Murata, T Yasujima… - The Journal of …, 2010 - Elsevier
Riboflavin transporter (RFT) 2 has recently been identified as a transporter that may be,
mainly based on the functional characteristics of its rat ortholog (rRFT2), involved in the …

Identification and functional characterization of rat riboflavin transporter 2

S Yamamoto, K Inoue, K Ohta, R Fukatsu… - Journal of …, 2009 - academic.oup.com
We have newly identified rat riboflavin transporter 2 (rRFT2) and its human orthologue
(hRFT2), and carried out detailed functional characterization of rRFT2. The mRNA of rRFT2 …

Identification and functional characterization of a novel human and rat riboflavin transporter, RFT1

A Yonezawa, S Masuda… - American Journal of …, 2008 - journals.physiology.org
Absorption of riboflavin is mediated by transporter (s). However, a mammalian riboflavin
transporter has yet to be identified. In the present study, the novel human and rat riboflavin …

[HTML][HTML] Identification and comparative functional characterization of a new human riboflavin transporter hRFT3 expressed in the brain

Y Yao, A Yonezawa, H Yoshimatsu, S Masuda… - The Journal of …, 2010 - Elsevier
We isolated cDNA coding a new human riboflavin transporter (hRFT) 3, which exhibits 86.7
and 44.1% amino acid identity with hRFT1 and hRFT2, respectively. It was predicted to have …

[HTML][HTML] Differential expression of human riboflavin transporters-1,-2, and-3 in polarized epithelia: a key role for hRFT-2 in intestinal riboflavin uptake

VS Subramanian, SB Subramanya, L Rapp… - … et Biophysica Acta (BBA …, 2011 - Elsevier
Transport of riboflavin (RF) across both the brush border membrane (BBM) and basolateral
membrane (BLM) of the polarized enterocyte occurs via specific carrier-mediated …

Role of cysteine residues in cell surface expression of the human riboflavin transporter-2 (hRFT2) in intestinal epithelial cells

VS Subramanian, L Rapp… - American Journal of …, 2011 - journals.physiology.org
The water-soluble vitamin B2 (riboflavin, RF) is an essential micronutrient for normal cell
function and survival. Recent studies have identified a role for the human riboflavin …

Functional involvement of RFVT3/SLC52A3 in intestinal riboflavin absorption

H Yoshimatsu, A Yonezawa, Y Yao… - American Journal …, 2014 - journals.physiology.org
Riboflavin, also known as vitamin B2, is transported across the biological membrane into
various organs by transport systems. Riboflavin transporter RFVT3 is expressed in the small …

Involvement of riboflavin transporter RFVT2/Slc52a2 in hepatic homeostasis of riboflavin in mice

Y Yao, A Yonezawa, H Yoshimatsu, T Omura… - European journal of …, 2013 - Elsevier
Riboflavin (vitamin B2) acts as an intermediary during various biochemical oxidation–
reduction reactions in the liver. Hepatic riboflavin homeostasis is suggested to be …

Molecular mechanisms mediating the adaptive regulation of intestinal riboflavin uptake process

VS Subramanian, A Ghosal, R Kapadia… - PLoS …, 2015 - journals.plos.org
The intestinal absorption process of vitamin B2 (riboflavin, RF) is carrier-mediated, and all
three known human RF transporters, ie, hRFVT-1,-2, and-3 (products of the SLC52A1, 2 & 3 …

Conditional (intestinal-specific) knockout of the riboflavin transporter-3 (RFVT-3) impairs riboflavin absorption

VS Subramanian, N Lambrecht… - American Journal of …, 2016 - journals.physiology.org
Riboflavin (RF) is indispensable for normal cell metabolism, proliferation, and growth. The
RFVT-3 protein (product of the Slc52a3 gene) is expressed in the gut with the expression …