Bone tissue engineering: recent advances and challenges

AR Amini, CT Laurencin… - Critical Reviews™ in …, 2012 - dl.begellhouse.com
The worldwide incidence of bone disorders and conditions has trended steeply upward and
is expected to double by 2020, especially in populations where aging is coupled with …

Functional biomaterials for bone regeneration: a lesson in complex biology

AR Armiento, LP Hatt… - Advanced Functional …, 2020 - Wiley Online Library
Bone is a hard yet dynamic tissue with remarkable healing capacities. Research to date has
greatly advanced the understanding of how bone heals and has led to marked success in …

Current approaches to bone tissue engineering: the interface between biology and engineering

JJ Li, M Ebied, J Xu, H Zreiqat - Advanced healthcare materials, 2018 - Wiley Online Library
The successful regeneration of bone tissue to replace areas of bone loss in large defects or
at load‐bearing sites remains a significant clinical challenge. Over the past few decades …

A review of biomaterials in bone defect healing, remaining shortcomings and future opportunities for bone tissue engineering: The unsolved challenge

T Winkler, FA Sass, GN Duda… - Bone & joint …, 2018 - boneandjoint.org.uk
Despite its intrinsic ability to regenerate form and function after injury, bone tissue can be
challenged by a multitude of pathological conditions. While innovative approaches have …

Bone scaffolds: an incorporation of biomaterials, cells, and biofactors

M Bahraminasab, M Janmohammadi… - ACS Biomaterials …, 2021 - ACS Publications
Large injuries to bones are still one of the most challenging musculoskeletal problems.
Tissue engineering can combine stem cells, scaffold biomaterials, and biofactors to aid in …

Bone tissue engineering

CRM Black, V Goriainov, D Gibbs, J Kanczler… - Current molecular …, 2015 - Springer
Medical advances have led to a welcome increase in life expectancy. However,
accompanying longevity introduces new challenges: increases in age-related diseases and …

Recent advances in bone tissue engineering scaffolds

S Bose, M Roy, A Bandyopadhyay - Trends in biotechnology, 2012 - cell.com
Bone disorders are of significant concern due to increase in the median age of our
population. Traditionally, bone grafts have been used to restore damaged bone. Synthetic …

Bone tissue engineering via growth factor delivery: from scaffolds to complex matrices

TM De Witte, LE Fratila-Apachitei… - Regenerative …, 2018 - academic.oup.com
In recent years, bone tissue engineering has emerged as a promising solution to the
limitations of current gold standard treatment options for bone related-disorders such as …

Advances in Bone tissue engineering: A fundamental review

BM Manzini, LMR Machado, PY Noritomi… - Journal of …, 2021 - Springer
Bone is a dynamic tissue that can always rebuild itself by modeling and remodeling to
maintain functionality. This tissue is responsible for several vital functions in the body, such …

Current advances for bone regeneration based on tissue engineering strategies

R Shi, Y Huang, C Ma, C Wu, W Tian - Frontiers of medicine, 2019 - Springer
Bone tissue engineering (BTE) is a rapidly developing strategy for repairing critical-sized
bone defects to address the unmet need for bone augmentation and skeletal repair. Effective …