Zero‐valence selenium‐enriched Prussian blue nanozymes reconstruct intestinal barrier against inflammatory bowel disease via inhibiting Ferroptosis and T cells …

D Zhu, H Wu, K Jiang, Y Xu, Z Miao… - Advanced Healthcare …, 2023 - Wiley Online Library
The structural disruption of mechanical barrier and dysfunction of immune barrier in
intestinal, are important factors, that aggravate inflammatory bowel disease (IBD). To tackle …

[HTML][HTML] Nanozyme-mediated catalytic nanotherapy for inflammatory bowel disease

J Zhao, W Gao, X Cai, J Xu, D Zou, Z Li, B Hu… - Theranostics, 2019 - ncbi.nlm.nih.gov
The overproduction of reactive oxygen species (ROS) is linked to inflammatory bowel
disease (IBD) and causes oxidative damage to DNA, proteins, and lipids. These ROS …

Prussian blue nanozyme with multienzyme activity reduces colitis in mice

J Zhao, X Cai, W Gao, L Zhang, D Zou… - … applied materials & …, 2018 - ACS Publications
The overproduction of reactive oxygen species (ROS) is central to the progression of
inflammatory bowel disease (IBD), which may be the potential therapeutic target. Prussian …

Oral metal‐free melanin nanozymes for natural and durable targeted treatment of inflammatory bowel disease (IBD)

Q Huang, Y Yang, Y Zhu, Q Chen, T Zhao, Z Xiao… - Small, 2023 - Wiley Online Library
Oral antioxidant nanozymes bring great promise for inflammatory bowel disease (IBD)
treatment. To efficiently eliminate reactive oxygen species (ROS), various metal‐based …

[HTML][HTML] Enzyme-like biomimetic oral-agent enabling modulating gut microbiota and restoring redox homeostasis to treat inflammatory bowel disease

Z Shi, X Li, J Chen, Z Dai, Y Zhu, T Wu, Q Liu, H Qin… - Bioactive Materials, 2024 - Elsevier
Reactive oxygen species (ROS), immune dysregulation-induced inflammatory outbreaks
and microbial imbalance play critical roles in the development of inflammatory bowel …

[HTML][HTML] A drug-free nanozyme for mitigating oxidative stress and inflammatory bowel disease

F Zeng, Y Shi, C Wu, J Liang, Q Zhong, K Briley… - Journal of …, 2022 - Springer
Inflammatory bowel disease (IBD) is an incurable disease of the gastrointestinal tract with a
lack of effective therapeutic strategies. The proinflammatory microenvironment plays a …

[HTML][HTML] Sulfasalazine-loaded nanoparticles for efficient inflammatory bowel disease therapy via ROS-scavenging strategy

S Lin, H Zhao, C Xu, P Zhang, X Mei, D Jiang - Materials & Design, 2023 - Elsevier
Inflammatory bowel disease (IBD) is a life-threatening organ dysfunction amplified by
complex interactions between genetic, environmental, and immune factors. Sulfasalazine …

Construction of pH‐Dependent Nanozymes with Oxygen Vacancies as the High‐Efficient Reactive Oxygen Species Scavenger for Oral‐Administrated Anti …

N Zhao, FE Yang, CY Zhao, SW Lv… - Advanced …, 2021 - Wiley Online Library
It is of great significance to eliminate excessive reactive oxygen species (ROS) for treating
inflammatory bowel disease (IBD). Herein, for the first time, a novel nanozyme NiCo2O4 …

Multifunctional two-dimensional Bi2Se3 nanodiscs for anti-inflammatory therapy of inflammatory bowel diseases

C Zhang, Q Li, J Shan, J Xing, X Liu, Y Ma, H Qian… - Acta Biomaterialia, 2023 - Elsevier
The overexpression of reactive oxygen and nitrogen species (RONS) in the colonic mucosa
destroys the mucosa and its barrier, accelerating the occurrence of inflammatory bowel …

Tannic acid and zinc ion coordination of nanase for the treatment of inflammatory bowel disease by promoting mucosal repair and removing reactive oxygen and …

C Zhang, Q Li, J Xing, Y Yang, M Zhu, L Lin, Y Yu… - Acta Biomaterialia, 2024 - Elsevier
Colon mucosal overexpression of reactive oxygen and nitrogen species (RONS) accelerates
the development of inflammatory bowel disease (IBD) and destroys the mucosa and its …