Cytokines produced by immune cells have been demonstrated to act on muscle stem cells
(MuSCs) and direct their fate and behavior during muscle repair and regeneration …

Muscle damage induces massive macrophage infiltration of the injury site, in which activated
pro‐inflammatory and anti‐inflammatory phenotypes (currently classified as M1 and M2 …

Macrophages drive muscle regeneration and repair by removing necrotic material and
producing key signaling molecules. The array of cytokines/growth factors produced by …

Adult skeletal muscle regenerates completely after a damage, thanks to the satellite cells, or
muscle stem cells (MuSCs), that implement the adult myogenic program. This program is …

Background Sequential accumulation of M1 and M2 macrophages is critical for skeletal
muscle recovery after an acute injury. While M1 accumulation is believed to rely on …

Macrophages are one of the first barriers of host defence against pathogens. Beyond their
role in innate immunity, macrophages play increasingly defined roles in orchestrating the …

Adult skeletal muscle regeneration results from activation, proliferation, and fusion of muscle
stem cells, such as myogenic precursor cells. Macrophages are consistently present in …

The presence of macrophages (MPs) is essential for skeletal muscle to properly regenerate
following injury. The aim of this study was the evaluation of MP profiles and their importance …

The skeletal muscle injury triggers the inflammatory response which is crucial for damaged
muscle fiber degradation and satellite cell activation. Immunodeficient mice are often used …

Skeletal muscle is one of the most sensitive tissues to mechanical loading, and unloading
inhibits the regeneration potential of skeletal muscle after injury. This study was designed to …