Increase in the practice of sport by more and more numerous people in the Western
countries is associated with an increase in muscle injuries, and in demand for improving …

Myeloid cells are critical to the development of fibrosis following muscle injury; however, the
mechanism of their role in fibrosis formation remains unclear. In this study, we demonstrate …

Macrophages have well-characterized roles in skeletal muscle repair and regeneration.
Relatively little is known regarding the role of resident macrophages in skeletal muscle …

Pronounced catabolic effects of proinflammatory cytokines in various tissues contribute to
local catabolism, with progressive atrophic alterations of the skeletal muscle in chronic …

Inflammation, an important phase of skeletal muscle healing, largely involves macrophages,
TGF‐β1, and the COX‐2 pathway. To improve our understanding of how these molecules …

We used an in vitro model to investigate whether macrophages stimulate satellite cells
proliferation. Satellite cells were obtained by tryptic digestion of adult muscle. Macrophages …

Muscle regeneration is the result of the concerted action of multiple cell types driven by the
temporarily controlled phenotype switches of infiltrating monocyte–derived macrophages …

Skeletal muscle is susceptible to injury following trauma, neurological dysfunction, and
genetic diseases. Skeletal muscle homeostasis is maintained by a pronounced regenerative …

Atrophy of skeletal muscle leads to decreases in myofiber size and nuclear number;
however, the effects of atrophic conditions on muscle precursor cells (MPC) are largely …

Numerous studies have pharmacologically modulated the muscle milieu in the hopes of
promoting muscle regeneration; however, the timing and duration of these interventions are …