Pharmacokinetic comparison of sustained-and immediate-release formulations of cilostazol after multiple oral doses in fed healthy male Korean volunteers
YH Kim, JL Ghim, JA Jung, SH Cho… - Drug Design …, 2015 - Taylor & Francis
Background A new extended-release form of cilostazol has recently been developed. This
study was conducted to compare the pharmacokinetic characteristics of sustained-release …
study was conducted to compare the pharmacokinetic characteristics of sustained-release …
Polymorphism of linezolid: A combined single-crystal, powder diffraction and NMR study
E Maccaroni, E Alberti, L Malpezzi, N Masciocchi… - International journal of …, 2008 - Elsevier
Linezolid (S)-N-[[3-(3-fluoro-4-morpholinylphenyl)-2-oxo-5-oxazolidinyl] methyl] acetamide
is one of the first commercially available (and most widely used) oxazolidinone antibiotics. It …
is one of the first commercially available (and most widely used) oxazolidinone antibiotics. It …
Relative bioavailability and effects of a high fat meal on single dose cilostazol pharmacokinetics
SL Bramer, WP Forbes - Clinical pharmacokinetics, 1999 - Springer
Objectives The objectives of this research were to (1) assess the relative bioavailability
following administration of a 100mg cilostazol suspension versus 100mg tablet;(2) assess …
following administration of a 100mg cilostazol suspension versus 100mg tablet;(2) assess …
Enhancement of ketoconazole dissolution rate by the liquisolid technique
MA Molaei, K Osouli-Bostanabad, K Adibkia… - Acta …, 2018 - sciendo.com
The study was conducted to enhance the dissolution rate of ketoconazole (KCZ)(a poorly
water-soluble drug) using the liquisolid technique. Microcrystalline cellulose, colloidal silica …
water-soluble drug) using the liquisolid technique. Microcrystalline cellulose, colloidal silica …
Phase I study of cilostazol. Safety evaluation at increasing single doses in healthy volunteers.
T Niki, H Mori - Arzneimittel-forschung, 1985 - europepmc.org
The safety and blood concentrations of the novel synthetic platelet aggregation inhibitor
cilostazol (6-[4-(1-cyclohexyl-1H-tetrazol-5-yl) butoxy]-3, 4-dihydro-2 (1H)-qui nolinone, OPC …
cilostazol (6-[4-(1-cyclohexyl-1H-tetrazol-5-yl) butoxy]-3, 4-dihydro-2 (1H)-qui nolinone, OPC …
Reprecipitation of poorly water-soluble cilostazol crystals using adsorbing carriers for enhanced dissolution and physicochemical modification
N Baek, GH Oh, C Park, TTT Tran, YJ Park, E Oh… - Journal of drug delivery …, 2018 - Elsevier
The aim of this new work was to improve the dissolution rate of poorly water-soluble
cilostazol (CLT) by adsorbing dissolved drug molecules onto the surface of undissolved …
cilostazol (CLT) by adsorbing dissolved drug molecules onto the surface of undissolved …
Formation, physical stability, and quantification of process-induced disorder in cryomilled samples of a model polymorphic drug
Y Hu, P Macfhionnghaile, V Caron, L Tajber… - Journal of …, 2013 - Elsevier
The formation and physical stability of amorphous sulfathiazole obtained from polymorphic
forms I and III by cryomilling was investigated by X‐ray powder diffraction (XRPD) and near …
forms I and III by cryomilling was investigated by X‐ray powder diffraction (XRPD) and near …
Improving dissolution properties by polymers and surfactants: A case study of celastrol
J Zha, Q Zhang, M Li, JR Wang, X Mei - Journal of Pharmaceutical Sciences, 2018 - Elsevier
Two polymorphs of celastrol were discovered and fully characterized by X-ray powder
diffraction, thermogravimetry analysis, and differential scanning calorimetry. The single …
diffraction, thermogravimetry analysis, and differential scanning calorimetry. The single …
Validated stability-indicating methods for determination of cilostazol in the presence of its degradation products according to the ICH guidelines
AS Fayed, MA Shehata, A Ashour, NY Hassan… - … of pharmaceutical and …, 2007 - Elsevier
Sensitive and selective stability-indicating assay methods (SIAMs) are suggested for the
determination of cilostazol (CIL) in the presence of its acid, alkaline and oxidative …
determination of cilostazol (CIL) in the presence of its acid, alkaline and oxidative …
Polymorphic characterization and compatibility study of clozapine: implications on its stability and some biopharmaceutics properties
SBT Dias, TG Nascimento, AFO Santos… - Journal of Thermal …, 2015 - Springer
Clozapine is an antipsychotic drug used for refractory schizophrenia and severe psychiatric
disorders associated with several side effects. Studies on standardization of raw material …
disorders associated with several side effects. Studies on standardization of raw material …