Suppressed release of clarithromycin from tablets by crystalline phase transition of metastable polymorph form I
S Fujiki, N Watanabe, Y Iwao, S Noguchi… - Journal of …, 2015 - Wiley Online Library
The pharmaceutical properties of clarithromycin (CAM) tablets containing the metastable
form I of crystalline CAM were investigated. Although the dissolution rate of form I was higher …
form I of crystalline CAM were investigated. Although the dissolution rate of form I was higher …
Osmotic pump tablets with solid dispersions synergized by hydrophilic polymers and mesoporous silica improve in vitro/in vivo performance of cilostazol
S Zhang, Y Sun, L Zhou, Z Jiang, X Yang… - International Journal of …, 2020 - Elsevier
The purpose of this study is to improve in vitro dissolution and in vivo bioavailability of the
poorly soluble drug cilostazol (CLT) through amorphous solid dispersion technology, and …
poorly soluble drug cilostazol (CLT) through amorphous solid dispersion technology, and …
Spectrophotometric determination of cilostazol in tablet dosage form
Purpose: To develop simple, rapid and selective spectrophotometric methods for the
determination of cilostazol in tablet dosage form. Methods: Cilostazol was dissolved in 50 …
determination of cilostazol in tablet dosage form. Methods: Cilostazol was dissolved in 50 …
Celecoxib: nicotinamide dissociation: using excipients to capture the cocrystal's potential
JF Remenar, ML Peterson, PW Stephens… - Molecular …, 2007 - ACS Publications
The cocrystal of celecoxib and nicotinamide (Cel: Nic) was crystallized from chloroform in a
1: 1 ratio, and the structure has been solved from powder X-ray diffraction data. The …
1: 1 ratio, and the structure has been solved from powder X-ray diffraction data. The …
The effect of recrystallization on the crystal growth, melting point and solubility of ketoconazole
C Viseras, II Salem, ICR Galan, AC Galan… - Thermochimica acta, 1995 - Elsevier
Variations in the physico-chemical properties of ketoconazole have been studied, following
polymorphic changes caused by fusion-cooling processes or by recrystallization in solvents …
polymorphic changes caused by fusion-cooling processes or by recrystallization in solvents …
[HTML][HTML] Characterization of recrystallized itraconazole prepared by cooling and anti-solvent crystallization
P Sriamornsak, K Burapapadh - asian journal of pharmaceutical sciences, 2015 - Elsevier
The objective of the present study was to alter the crystal habit of itraconazole (ITZ) by
cooling and anti-solvent crystallization and characterize its properties. ITZ was recrystallized …
cooling and anti-solvent crystallization and characterize its properties. ITZ was recrystallized …
Enhancement of wettability and dissolution properties of cilostazol using the supercritical antisolvent process: effect of various additives
The aim of this study was to improve wettability and dissolution rate of a poorly water-soluble
drug, cilostazol, using the supercritical antisolvent (SAS) process. The solid state of particles …
drug, cilostazol, using the supercritical antisolvent (SAS) process. The solid state of particles …
[HTML][HTML] Hydrolytic degradation profile and RP-HPLC estimation of cilostazol in tablet dosage form
PK Basniwal, PK Shrivastava, D Jain - Indian journal of …, 2008 - ncbi.nlm.nih.gov
A simple, selective, precise and stability-indicating high-performance liquid-
chromatographic method of analysis of cilostazol in pharmaceutical dosage form was …
chromatographic method of analysis of cilostazol in pharmaceutical dosage form was …
Cocrystal Synthesis through Crystal Structure Prediction
YA Abramov, L Iuzzolino, Y Jin, G York… - Molecular …, 2023 - ACS Publications
Crystal structure prediction (CSP) is an invaluable tool in the pharmaceutical industry
because it allows to predict all the possible crystalline solid forms of small-molecule active …
because it allows to predict all the possible crystalline solid forms of small-molecule active …
Pharmacokinetics of multiple‐dose oral cilostazol in middle‐age and elderly men and women
A Suri, WP Forbes, SL Bramer - The Journal of Clinical …, 1998 - Wiley Online Library
Cilostazol is being developed for the treatment of intermittent claudication due to peripheral
arterial disease (PAD). This study was conducted to investigate the effects of age and …
arterial disease (PAD). This study was conducted to investigate the effects of age and …