A drug-free nanozyme for mitigating oxidative stress and inflammatory bowel disease
F Zeng, Y Shi, C Wu, J Liang, Q Zhong, K Briley… - Journal of …, 2022 - Springer
Inflammatory bowel disease (IBD) is an incurable disease of the gastrointestinal tract with a
lack of effective therapeutic strategies. The proinflammatory microenvironment plays a …
lack of effective therapeutic strategies. The proinflammatory microenvironment plays a …
Rational design of orally administered cascade nanozyme for inflammatory bowel disease therapy
Y Yu, X Zhao, X Xu, C Cai, X Tang, Q Zhang… - Advanced …, 2023 - Wiley Online Library
Inflammatory bowel disease (IBD) affects millions of individuals worldwide annually. Enteric
reactive oxygen species (ROS) play critical roles in the physiology and pathology of IBD …
reactive oxygen species (ROS) play critical roles in the physiology and pathology of IBD …
Orally administration of cerium oxide nanozyme for computed tomography imaging and anti-inflammatory/anti-fibrotic therapy of inflammatory bowel disease
Y Cao, K Cheng, M Yang, Z Deng, Y Ma, X Yan… - Journal of …, 2023 - Springer
Background Inflammatory bowel disease (IBD) is a chronic nonspecific disease with
unknown etiology. Currently, the anti-inflammatory therapeutic approaches have achieved a …
unknown etiology. Currently, the anti-inflammatory therapeutic approaches have achieved a …
[HTML][HTML] Gold nanoparticles-embedded ceria with enhanced antioxidant activities for treating inflammatory bowel disease
M Li, J Liu, L Shi, C Zhou, M Zou, D Fu, Y Yuan, C Yao… - Bioactive Materials, 2023 - Elsevier
The excessive reactive oxygen species (ROS) is a hallmark associated with the initiation
and progression of inflammatory bowel disease (IBD), which execrably form a vicious cycle …
and progression of inflammatory bowel disease (IBD), which execrably form a vicious cycle …
Construction of pH‐Dependent Nanozymes with Oxygen Vacancies as the High‐Efficient Reactive Oxygen Species Scavenger for Oral‐Administrated Anti …
N Zhao, FE Yang, CY Zhao, SW Lv… - Advanced …, 2021 - Wiley Online Library
It is of great significance to eliminate excessive reactive oxygen species (ROS) for treating
inflammatory bowel disease (IBD). Herein, for the first time, a novel nanozyme NiCo2O4 …
inflammatory bowel disease (IBD). Herein, for the first time, a novel nanozyme NiCo2O4 …
Oral nanozyme-engineered probiotics for the treatment of ulcerative colitis
H Zhao, Y Du, L Liu, Y Du, K Cui, P Yu, L Li… - Journal of Materials …, 2022 - pubs.rsc.org
Probiotic-based therapy for ulcerative colitis (UC) is a novel and promising approach that
has gained much popularity in recent years. However, probiotics may be easily captured …
has gained much popularity in recent years. However, probiotics may be easily captured …
[HTML][HTML] Nanozyme-mediated catalytic nanotherapy for inflammatory bowel disease
J Zhao, W Gao, X Cai, J Xu, D Zou, Z Li, B Hu… - Theranostics, 2019 - ncbi.nlm.nih.gov
The overproduction of reactive oxygen species (ROS) is linked to inflammatory bowel
disease (IBD) and causes oxidative damage to DNA, proteins, and lipids. These ROS …
disease (IBD) and causes oxidative damage to DNA, proteins, and lipids. These ROS …
Polydopamine modified ceria nanorods alleviate inflammation in colitis by scavenging ROS and regulating macrophage M2 polarization
Background Inflammatory bowel disease (IBD) is closely related to higher intracellular
oxidative stress. Therefore, developing a novel method to scavenge the harmful reactive …
oxidative stress. Therefore, developing a novel method to scavenge the harmful reactive …
An oral nano-antioxidant for targeted treatment of inflammatory bowel disease by regulating macrophage polarization and inhibiting ferroptosis of intestinal cells
J Yang, Y Bai, S Shen, X Tao, C Ma, B Fu, Q Dai… - Chemical Engineering …, 2023 - Elsevier
Inflammatory bowel disease (IBD) is a chronic inflammatory disease that characterized by
excessive reactive oxygen species (ROS) and high ferroptosis. The ROS plays an essential …
excessive reactive oxygen species (ROS) and high ferroptosis. The ROS plays an essential …
Probiotic‐inspired nanomedicine restores intestinal homeostasis in colitis by regulating redox balance, immune responses, and the Gut Microbiome
Microbiota‐based therapeutics offer innovative strategies to treat inflammatory bowel
diseases (IBDs). However, the poor clinical outcome so far and the limited flexibility of the …
diseases (IBDs). However, the poor clinical outcome so far and the limited flexibility of the …