Readily Available Oral Prebiotic Protein Reactive Oxygen Species Nanoscavengers for Synergistic Therapy of Inflammation and Fibrosis in Inflammatory Bowel …
Y Yu, D Yang, B Lin, L Zhu, C Li, X Li - ACS nano, 2024 - ACS Publications
A significant gap exists in the demand for safe and effective drugs for inflammatory bowel
disease (IBD), and its associated intestinal fibrosis. As oxidative stress plays a central role in …
disease (IBD), and its associated intestinal fibrosis. As oxidative stress plays a central role in …
Bi-functional astaxanthin macromolecular nanocarriers to alleviate dextran sodium sulfate-induced inflammatory bowel disease
Dextran sulfate sodium is one of the important members in the field of polysaccharide
biotechnology, which can induce inflammatory bowel disease (IBD) in the gastrointestinal …
biotechnology, which can induce inflammatory bowel disease (IBD) in the gastrointestinal …
Payload‐free protein nanoparticles target inflamed colons to restore intestinal barrier integrity for effectively treating inflammatory bowel diseases
M Yang, H Shen, S Zhong, Z Xu, X Liu, W Wu… - …, 2024 - Wiley Online Library
Anti‐inflammatory compounds, delivered as a payload to the gastrointestinal tract (GIT) by
carriers, still cannot treat inflammatory bowel diseases without avoiding side effects. Here …
carriers, still cannot treat inflammatory bowel diseases without avoiding side effects. Here …
Polyphenolic Nanoparticle-Modified Probiotics for Microenvironment Remodeling and Targeted Therapy of Inflammatory Bowel Disease
Q Hu, J Li, T Wang, X Xu, Y Duan, Y Jin - ACS nano, 2024 - ACS Publications
Inflammatory bowel diseases (IBDs) refer to multifaceted disorders in the intestinal
microenvironment and microbiota homeostasis. In view of the broad bioactivity and high …
microenvironment and microbiota homeostasis. In view of the broad bioactivity and high …
Microenvironment responsive pod-structured astaxanthin nanocarrier for ameliorating inflammatory bowel disease
J Wang, Y Chen, L Han, S Xia, X Zhang, P Xue… - Chinese Chemical …, 2024 - Elsevier
Anti-inflammatory drugs targeting inflammatory bowel disease (IBD) have attracted
considerable attention but still face low therapeutic outcomes and frequent side effects …
considerable attention but still face low therapeutic outcomes and frequent side effects …
An orally-administered nanotherapeutics with carbon monoxide supplying for inflammatory bowel disease therapy by scavenging oxidative stress and restoring gut …
X Zhang, Z Yuan, J Wu, Y He, G Lu, D Zhang, Y Zhao… - ACS …, 2023 - ACS Publications
Traditional drug-based treatments for inflammatory bowel disease (IBD) have significant
limitations due to their potential off-target systemic side-effects. Currently, there is a lack of …
limitations due to their potential off-target systemic side-effects. Currently, there is a lack of …
[HTML][HTML] Sulfasalazine-loaded nanoparticles for efficient inflammatory bowel disease therapy via ROS-scavenging strategy
S Lin, H Zhao, C Xu, P Zhang, X Mei, D Jiang - Materials & Design, 2023 - Elsevier
Inflammatory bowel disease (IBD) is a life-threatening organ dysfunction amplified by
complex interactions between genetic, environmental, and immune factors. Sulfasalazine …
complex interactions between genetic, environmental, and immune factors. Sulfasalazine …
A proresolving peptide nanotherapy for site‐specific treatment of inflammatory bowel disease by regulating proinflammatory microenvironment and gut microbiota
C Li, Y Zhao, J Cheng, J Guo, Q Zhang… - Advanced …, 2019 - Wiley Online Library
The incidence and prevalence of inflammatory bowel disease (IBD) increases steadily
worldwide. There is an urgent need for effective and safe IBD therapies. Accelerated …
worldwide. There is an urgent need for effective and safe IBD therapies. Accelerated …
Mucoadhesive probiotic backpacks with ROS nanoscavengers enhance the bacteriotherapy for inflammatory bowel diseases
Inflammatory bowel diseases (IBDs) are often associated with elevated levels of reactive
oxygen species (ROS) and highly dysregulated gut microbiota. In this study, we synthesized …
oxygen species (ROS) and highly dysregulated gut microbiota. In this study, we synthesized …
Attenuation of inflammatory bowel disease by oral administration of mucoadhesive polydopamine-coated yeast β-glucan via ROS scavenging and gut microbiota …
F Yang, Y Su, C Yan, T Chen, PCK Cheung - Journal of …, 2024 - Springer
Abstract Treatment for inflammatory bowel disease (IBD) is challenging since current anti-
inflammatory and immunosuppressive therapies do not address the underlying causes of …
inflammatory and immunosuppressive therapies do not address the underlying causes of …
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