Nerve growth factor (NGF) antagonism is on the verge of becoming a powerful analgesic
treatment for numerous conditions, including osteoarthritis and lower back pain. This review …

Chronic pain presents a huge economic and social burden, with existing treatments largely
unable to satisfy medical needs. Recently, studies have shown that nerve growth factor …

Nerve growth factor (NGF) is a neurotrophic protein essential for the growth, differentiation,
and survival of sympathetic and sensory afferent neurons during development. A substantial …

Nerve growth factor (NGF) is a neurotrophin that activates nociceptive neurons to transmit
pain signals from the peripheral to the central nervous system and that exerts its effects on …

Nerve growth factor (NGF) is central to the development and functional regulation of sensory
neurons that signal the first events that lead to pain. These sensory neurons, called …

It is unanimously accepted that there is an unmet need for pain medications that are both
effective and safe. Unfortunately, no really novel analgesics have been approved over the …

Nerve growth factor (NGF) is critical for the development and maintenance of sympathetic
and sensory neurons in the developing nervous system, including nociceptors. In the adult …

Nerve growth factor (NGF) is the founding member of the neurotrophins family of proteins. It
was discovered more than half a century ago through its ability to promote sensory and …

Nerve growth factor (NGF) was identified originally as a survival factor for sensory and
sympathetic neurons in the developing nervous system. In adults, NGF is not required for …

Neurotrophic factors have an established developmental role in regulating the survival and
specification of sensory neurons. However, these factors continue to exert an important …