Tissue-resident stem cells promote breast cancer growth and metastasis

FL Muehlberg, YH Song, A Krohn, SP Pinilla… - …, 2009 - academic.oup.com
Mesenchymal stem cells derived from bone marrow have recently been described to
localize to breast carcinomas and to integrate into the tumor-associated stroma. In the …

Breast cancer stem cells are regulated by mesenchymal stem cells through cytokine networks

S Liu, C Ginestier, SJ Ou, SG Clouthier, SH Patel… - Cancer research, 2011 - AACR
We have used in vitro and mouse xenograft models to examine the interaction between
breast cancer stem cells (CSC) and bone marrow–derived mesenchymal stem cells (MSC) …

Mesenchymal stem cells from primary breast cancer tissue promote cancer proliferation and enhance mammosphere formation partially via EGF/EGFR/Akt pathway

X Yan, C Fu, L Chen, J Qin, Q Zeng, H Yuan… - Breast cancer research …, 2012 - Springer
Mesenchymal stem cells (MSCs) play a critical role in promoting cancer progression.
However, it is not clear whether MSCs are located in breast cancer tissues and correlated …

Human adipose-derived mesenchymal stem cell-secreted CXCL1 and CXCL8 facilitate breast tumor growth by promoting angiogenesis

Y Wang, J Liu, Q Jiang, J Deng, F Xu, X Chen… - Stem Cells, 2017 - academic.oup.com
Autologous adipose tissue or adipose tissue with additive adipose-derived mesenchymal
stem cells (ADSCs) is used in the breast reconstruction of breast cancer patients who …

Tissue resident stem cells produce CCL5 under the influence of cancer cells and thereby promote breast cancer cell invasion

S Pinilla, E Alt, FJA Khalek, C Jotzu, F Muehlberg… - Cancer letters, 2009 - Elsevier
In the present study, we investigated whether human adipose tissue derived stem cells
(hASCs) could enhance tumor invasion and whether these hASCs could be a potential …

Bone marrow-derived mesenchymal stem cells promote growth and angiogenesis of breast and prostate tumors

T Zhang, YW Lee, YF Rui, TY Cheng, XH Jiang… - Stem cell research & …, 2013 - Springer
Abstract Introduction Mesenchymal stem cells (MSCs) are known to migrate to tumor tissues.
This behavior of MSCs has been exploited as a tumor-targeting strategy for cell-based …

Bone marrow–derived fibroblasts are a functionally distinct stromal cell population in breast cancer

Y Raz, N Cohen, O Shani, RE Bell… - Journal of Experimental …, 2018 - rupress.org
Cancer-associated fibroblasts (CAFs) are highly prominent in breast tumors, but their
functional heterogeneity and origin are still largely unresolved. We report that bone marrow …

Mesenchymal stem cells promote mammary cancer cell migration in vitro via the CXCR2 receptor

JL Halpern, A Kilbarger, CC Lynch - Cancer letters, 2011 - Elsevier
Bone metastasis is a common event during breast cancer progression. Recently,
mesenchymal stem cells (MSCs) have been implicated in the metastasis of primary …

Adipose tissue derived stem cells differentiate into carcinoma-associated fibroblast-like cells under the influence of tumor derived factors

C Jotzu, E Alt, G Welte, J Li, BT Hennessy… - Cellular oncology, 2011 - Springer
Background Carcinoma-associated fibroblasts (CAF) are considered to contribute to tumor
growth, invasion and metastasis. However, the cell type of origin remains unknown. Since …

[HTML][HTML] Both human and mouse mesenchymal stem cells promote breast cancer metastasis

SM Albarenque, RM Zwacka, A Mohr - Stem cell research, 2011 - Elsevier
Cell therapy has the potential to offer novel treatment modalities for a number of diseases
including cancer, and stem cells and in particular mesenchymal stem cells (MSCs) have …