[HTML][HTML] Characterization, mechanism of action and optimization of activity of a novel peptide-peptoid hybrid against bacterial pathogens involved in canine skin …

I Greco, AP Emborg, B Jana, N Molchanova, A Oddo… - Scientific Reports, 2019 - nature.com
Integumentary infections like pyoderma represent the main reason for antimicrobial
prescription in dogs. Staphylococcus pseudintermedius and Pseudomonas aeruginosa are …

[HTML][HTML] Structure–Activity Study, Characterization, and Mechanism of Action of an Antimicrobial Peptoid D2 and Its d- and l-Peptide Analogues

I Greco, JE Hansen, B Jana, N Molchanova, A Oddo… - Molecules, 2019 - mdpi.com
Methicillin-resistant Staphylococcus pseudintermedius (MRSP) constitutes an emerging
health problem for companion animals in veterinary medicine. Therefore, discovery of novel …

[HTML][HTML] Antibacterial Activity of Novel Cationic Peptides against Clinical Isolates of Multi-Drug Resistant Staphylococcus pseudintermedius from Infected Dogs

MF Mohamed, GK Hammac, L Guptill, MN Seleem - PloS one, 2014 - journals.plos.org
Staphylococcus pseudintermedius is a major cause of skin and soft tissue infections in
companion animals and has zoonotic potential. Additionally, methicillin-resistant S …

[HTML][HTML] Evaluation of short-chain antimicrobial peptides with combined antimicrobial and anti-inflammatory bioactivities for the treatment of zoonotic skin pathogens …

Q Tang, C Yang, W Li, Y Zhang, X Wang… - Frontiers in …, 2021 - frontiersin.org
The incidence of zoonotic Staphylococcus pseudintermedius and Microsporum canis
infections is rapidly growing worldwide in the context of an increasing frequency of close …

[HTML][HTML] In vitro adme properties of two novel antimicrobial peptoid-based compounds as potential agents against canine pyoderma

I Greco, BD Hummel, J Vasir, JL Watts, J Koch… - Molecules, 2018 - mdpi.com
Antimicrobial peptides (AMPs) hold promise as the next generation of antimicrobial agents,
but often suffer from rapid degradation in vivo. Modifying AMPs with non-proteinogenic …

[HTML][HTML] In vitro efficiency of antimicrobial peptides against Staphylococcal pathogens associated with canine pyoderma

M Jarosiewicz, K Garbacz, D Neubauer, W Kamysz - Animals, 2020 - mdpi.com
Simple Summary Coagulase-positive staphylococci (CoPS) are predominant pathogens in
canine pyoderma, especially S. pseudintermedius and S. aureus. The antimicrobial …

[HTML][HTML] In Vitro/Vivo Mechanisms of Antibacterial Peptide NZ2114 against Staphylococcus pseudintermedius and Its Biofilms

S Zhang, N Yang, R Mao, Y Hao, D Teng, J Wang - Antibiotics, 2024 - mdpi.com
Staphylococcus pseudintermedius is an opportunistic pathogen commonly found in canines,
and has garnered escalating interest due to its potential for zoonotic transmission and …

[HTML][HTML] Bacteriocins Revitalize Non-Effective Penicillin G to Overcome Methicillin-Resistant Staphylococcus pseudintermedius

KV Ovchinnikov, C Kranjec, T Thorstensen, H Carlsen… - Antibiotics, 2022 - mdpi.com
The rise of antibiotic-resistant bacteria is among the biggest challenges in human and
veterinary medicine. One of the major factors that contributes to resistance is use of frontline …

Antimicrobial, hemolytic, and cytotoxic activities of β‐peptoid–peptide hybrid oligomers: Improved properties compared to natural AMPs

CA Olsen, HL Ziegler, HM Nielsen… - …, 2010 - Wiley Online Library
While natural host-defense antimicrobial peptides (AMPs) and analogues thereof have been
investigated intensely in the last two decades with the purpose of combating the still …

Tailoring Cytotoxicity of Antimicrobial Peptidomimetics with High Activity against Multidrug-Resistant Escherichia coli

RD Jahnsen, A Sandberg-Schaal… - Journal of medicinal …, 2014 - ACS Publications
Infections with multidrug-resistant pathogens are an increasing concern for public health.
Recently, subtypes of peptide–peptoid hybrids were demonstrated to display potent activity …