The care of children with lupus nephritis (LN) has changed dramatically over the past 50 y.
The majority of patients with childhood-onset systemic lupus erythematosus (cSLE) develop …

Lupus nephritis (LN) is one of the major clinical manifestations of systemic lupus
erythematosus (SLE) which occurs frequently in the early stages of pediatric-onset cases …

Systemic lupus erythematosus (SLE) is a multiorgan autoimmune disease with increasing
mortality that often targets young women and children of United States minorities. Childhood …

Background Children with lupus have a higher chance of nephritis and worse kidney
outcome than adult patients. Methods We retrospectively analyzed clinical presentation …

Background Lupus nephritis (LN) has variable prevalence, severity, and outcomes across
the world. Objectives This review compares the outcomes of childhood LN in low-and middle …

Lupus nephritis is an important manifestation of systemic lupus erythematosus, which leads
to chronic kidney disease, kidney failure, and can result in mortality. About 35%–60% of …

Results Mean age at diagnosis was 12.3±2.9 years with median follow-up of 5 years. Poor
renal function (estimated GFR< 60 ml/min per 1.73 m 2) and nephrotic proteinuria at …

Lupus nephritis (LN) is more common and severe in childhood-onset systemic lupus
erythematosus (SLE) than in adults. It is one of the major causes of acute kidney injury (AKI) …

Childhood-onset systemic lupus erythematosus (cSLE) is a severe multisystem autoimmune
disease. Renal involvement occurs in the majority of cSLE patients and is often fatal. Renal …

There is still a significant morbidity and mortality associated with childhood‐onset systemic
lupus erythematosus (SLE), despite an increasing armamentarium of immunosuppressive …