Conditioning on intermediates in perinatal epidemiology
TJ VanderWeele, SL Mumford, EF Schisterman - Epidemiology, 2012 - journals.lww.com
It is common practice in perinatal epidemiology to calculate gestational-age-specific or birth-
weight-specific associations between an exposure and a perinatal outcome. Gestational age …
weight-specific associations between an exposure and a perinatal outcome. Gestational age …
On the pitfalls of adjusting for gestational age at birth
Preterm delivery is a powerful predictor of newborn morbidity and mortality. Such problems
are due to not only immaturity but also the pathologic factors (such as infection) that cause …
are due to not only immaturity but also the pathologic factors (such as infection) that cause …
A principled approach to mediation analysis in perinatal epidemiology
For many research questions in perinatal epidemiology, gestational age is a mediator that
features the causal pathway between exposure and outcome. A mediator is an intermediate …
features the causal pathway between exposure and outcome. A mediator is an intermediate …
Confounding, causality, and confusion: the role of intermediate variables in interpreting observational studies in obstetrics
CV Ananth, EF Schisterman - American journal of obstetrics and …, 2017 - Elsevier
Prospective and retrospective cohorts and case-control studies are some of the most
important study designs in epidemiology because, under certain assumptions, they can …
important study designs in epidemiology because, under certain assumptions, they can …
Negative control exposures in epidemiologic studies
We thank George Davey Smith1 for his thoughtful comments on our paper2 and for drawing
attention to his previous use of a negative control exposure. We agree with his interpretation …
attention to his previous use of a negative control exposure. We agree with his interpretation …
The curse of the perinatal epidemiologist: inferring causation amidst selection
Abstract Purpose of Review Human reproduction is a common process and one that unfolds
over a relatively short time, but pregnancy and birth processes are challenging to study …
over a relatively short time, but pregnancy and birth processes are challenging to study …
Quantification of collider‐stratification bias and the birthweight paradox
BW Whitcomb, EF Schisterman… - Paediatric and …, 2009 - Wiley Online Library
The 'birthweight paradox'describes the phenomenon whereby birthweight‐specific mortality
curves cross when stratified on other exposures, most notably cigarette smoking. The …
curves cross when stratified on other exposures, most notably cigarette smoking. The …
Reinterpreting the effects of maternal smoking on infant birthweight and perinatal mortality: a multivariate approach to birthweight standardization
PB ENGLISH, B ESKENAZI - International Journal of …, 1992 - academic.oup.com
Infants of women who smoke during pregnancy have lower birthweights and have been
observed to have higher rates of perinatal mortality than infants of non-smokers. It is not …
observed to have higher rates of perinatal mortality than infants of non-smokers. It is not …
The birth weight “paradox” uncovered?
S Hernández-Díaz, EF Schisterman… - American journal of …, 2006 - academic.oup.com
Low birth weight (LBW) infants have lower infant mortality in groups in which LBW is most
frequent. For example, in 1991, US infants born to smokers had higher risks of both LBW …
frequent. For example, in 1991, US infants born to smokers had higher risks of both LBW …
Educational note: addressing special cases of bias that frequently occur in perinatal epidemiology
AM Neophytou, MA Kioumourtzoglou… - International journal …, 2021 - academic.oup.com
The epidemiologic study of pregnancy and birth outcomes may be hindered by several
unique and challenging issues. Pregnancy is a time-limited period in which severe cohort …
unique and challenging issues. Pregnancy is a time-limited period in which severe cohort …