Systematic reviews of observational studies of aetiology are especially important. Studies of
this type tend to be limited in size and thus by examining multiple similar studies …

Systematic reviews are a type of evidence synthesis in which authors develop explicit
eligibility criteria, collect all the available studies that meet these criteria, and summarize …

Figure 1 Distinguished statistician Karl Pearson is seen as the first medical researcher to
use formal techniques to combine data from different studies studies are needed. For …

Systematic literature reviews including meta-analyses are invaluable scientific activities. The
rationale for such reviews is well established. Health care providers, researchers, and policy …

Objectives To review current practice in the analysis and reporting of epidemiological
research and to identify limitations. Design Examination of articles published in January …

This document updates the existing Agency for Healthcare Research and Quality (AHRQ)
Evidence-based Practice Center (EPC) Methods Guide for Effectiveness and Comparative …

Although randomized controlled trials provide the highest level of evidence for causation,
many clinical issues cannot be addressed using experimental study design. Examples that …

Many clinicians report that they cannot read the medical literature critically. To address this
difficulty, we provide a primer of clinical research for clinicians and researchers alike …

Objective To develop a study Design Algorithm for Medical Literature on Intervention (DAMI)
and test its interrater reliability, construct validity, and ease of use. Study Design and Setting …

The Division of General Internal Medicine, University of Alberta and The Institute of Health
Economics, Edmonton, Alberta, Canada. Correspondence: Dr F McAlister, 2E3. 24 WMC …