Two optimized antimicrobial peptides with therapeutic potential for clinical antibiotic-resistant Staphylococcus aureus

C Li, C Zhu, B Ren, X Yin, SH Shim, Y Gao… - European journal of …, 2019 - Elsevier
The rapid increase of Methicillin-resistant Staphylococcus aureus (MRSA) infections and the
cross-resistance of MRSA to other antibiotics create an urgent demand for new therapeutic …

Efficacy and toxicity studies of novel α-MSH analogues with antibiofilm action and β-lactam resensitization potential against MRSA

S Mumtaz, S Behera, S Joshi… - ACS Infectious …, 2022 - ACS Publications
Methicillin-resistant Staphylococcus aureus (MRSA), a biofilm-forming recalcitrant pathogen
with a multidrug-resistant profile, poses a pandemic threat to human health and is the …

Design of a novel analogue peptide with potent antibiofilm activities against Staphylococcus aureus based upon a sapecin B-derived peptide

N Akhash, A Farajzadeh Sheikh, Z Farshadzadeh - Scientific Reports, 2024 - nature.com
Nowadays, antimicrobial peptides are promising to confront the existing global crisis of
antibiotic resistance. Here, a novel analogue peptide (mKLK) was designed based upon a D …

A peptide factor secreted by Staphylococcus pseudintermedius exhibits properties of both bacteriocins and virulence factors

B Wladyka, M Piejko, M Bzowska, P Pieta, M Krzysik… - Scientific reports, 2015 - nature.com
Staphylococcus pseudintermedius is a common commensal bacterium colonizing the skin
and mucosal surfaces of household animals. However, it has recently emerged as a …

Design and Synthesis of a Novel Cationic Peptide with Potent and Broad‐Spectrum Antimicrobial Activity

WP Liu, YH Chen, X Ming… - BioMed Research …, 2015 - Wiley Online Library
Antibacterial and antifungal peptides have increasingly been used to combat the antibiotic‐
resistant microbes in recent years. KW‐13, a novel cationic α‐helical antibacterial peptide …

A Bioengineered Nisin Derivative to Control Biofilms of Staphylococcus pseudintermedius

D Field, N Gaudin, F Lyons, PM O'Connor, PD Cotter… - PLoS …, 2015 - journals.plos.org
Antibiotic resistance and the shortage of novel antimicrobials are among the biggest
challenges facing society. One of the major factors contributing to resistance is the use of …

A New Synthetic Peptide Having Two Target of Antibacterial Action in E. coli ML35

A Barreto-Santamaría, H Curtidor… - Frontiers in …, 2016 - frontiersin.org
The increased resistance of microorganisms to the different antimicrobials available to today
has highlighted the need to find new therapeutic agents, including natural and/or synthetic …

A new high-yielding antimicrobial peptide NZX and its antibacterial activity against Staphylococcus hyicus in vitro/vivo

H Liu, N Yang, R Mao, D Teng, Y Hao, X Wang… - Applied microbiology …, 2020 - Springer
Staphylococcus hyicus, considered as a leading pathogen of exudative epidermitis, is a
serious threat to humans and animals. The emergency of bacterial resistance to antibiotics …

Antimicrobial Peptides as Anti-Infectives against Staphylococcus epidermidis

S Agarwal, G Sharma, S Dang, S Gupta… - Medical Principles and …, 2016 - karger.com
Staphylococcus epidermidis has emerged as the main causative agent for graft-related and
nosocomial infections. Rampant use of antibiotics and biofilm formed by the organism …

The bactericidal and antibiofilm effects of a lysine-substituted hybrid peptide, CM-10K14K, on biofilm-forming Staphylococcus epidermidis

N Klubthawee, M Wongchai, R Aunpad - Scientific Reports, 2023 - nature.com
Staphylococci, notably biofilm-forming Staphylococcus epidermidis, have been recognized
as global nosocomial pathogens in medical device-related infections. Their potential to …