[HTML][HTML] The bactericidal and antibiofilm effects of a lysine-substituted hybrid peptide, CM-10K14K, on biofilm-forming Staphylococcus epidermidis

N Klubthawee, M Wongchai, R Aunpad - Scientific Reports, 2023 - nature.com
Staphylococci, notably biofilm-forming Staphylococcus epidermidis, have been recognized
as global nosocomial pathogens in medical device-related infections. Their potential to …

Novel therapies based on cationic antimicrobial peptides

H Anne Pereira - Current pharmaceutical biotechnology, 2006 - ingentaconnect.com
Cationic antimicrobial peptides serve as critical defense molecules protecting the host from
invading bacteria, viruses and fungi. These antimicrobial peptides are widely distributed in …

[HTML][HTML] Antibacterial and anti-inflammatory activity of an antimicrobial peptide synthesized with D amino acids

J Brunetti, V Carnicelli, A Ponzi, A Di Giulio, AR Lizzi… - Antibiotics, 2020 - mdpi.com
The peptide SET-M33 is a molecule synthesized in tetra-branched form which is being
developed as a new antibiotic against Gram-negative bacteria. Its isomeric form with D …

Design and mechanism of action of a novel bacteria-selective antimicrobial peptide from the cell-penetrating peptide Pep-1

WL Zhu, H Lan, IS Park, JI Kim, HZ Jin, KS Hahm… - Biochemical and …, 2006 - Elsevier
Here, we report the successful design of a novel bacteria-selective antimicrobial peptide,
Pep-1-K (KKTWWKTWWTKWSQPKKKRKV). Pep-1-K was designed by replacing Glu-2, Glu …

Antimicrobial activity of different antimicrobial peptides (AMPs) against clinical methicillin-resistant Staphylococcus aureus (MRSA)

E Ciandrini, G Morroni, D Arzeni… - Current topics in …, 2018 - ingentaconnect.com
Background: Antimicrobial research is being focused to look for more effective therapeutics
against antibiotic-resistant infections caused by methicillin-resistant Staphylococcus aureus …

[HTML][HTML] Bioactive antimicrobial peptides: A new weapon to counteract zoonosis

L Zupin, CA Santos-Silva, ARH Al Mughrbi, LMB Vilela… - Microorganisms, 2022 - mdpi.com
Zoonoses have recently become the center of attention of the general population and
scientific community. Notably, more than 30 new human pathogens have been identified in …

Antibacterial activity and dual mechanisms of peptide analog derived from cell-penetrating peptide against Salmonella typhimurium and Streptococcus pyogenes

L Li, YH Shi, MJ Cheserek, GF Su, GW Le - Applied microbiology and …, 2013 - Springer
A number of research have proven that antimicrobial peptides are of greatest potential as a
new class of antibiotics. Antimicrobial peptides and cell-penetrating peptides share some …

KKKKPLFGLFFGLF: a cationic peptide designed to exert antibacterial activity

E Duval, C Zatylny, M Laurencin, M Baudy-Floc'h… - Peptides, 2009 - Elsevier
With 14 residues organized as two domains linked by a single proline, the de novo peptide
called K4 was designed, using Antimicrobial Peptide Database, to exert antibacterial activity …

Discovery of an ultra-short linear antibacterial tetrapeptide with anti-MRSA activity from a structure–activity relationship study

QY Lau, FM Ng, JWD Cheong, YYA Yap… - European journal of …, 2015 - Elsevier
The overuse and misuse of antibiotics has resulted in the emergence of drug-resistant
pathogenic bacteria, including meticillin-resistant Staphylococcus aureus (MRSA), the …

Database screening and in vivo efficacy of antimicrobial peptides against methicillin-resistant Staphylococcus aureus USA300

J Menousek, B Mishra, ML Hanke, CE Heim… - International journal of …, 2012 - Elsevier
Natural antimicrobial peptides (AMPs) are promising candidates for developing a generation
of new antimicrobials to meet the challenge of antibiotic-resistant pathogens such as …