Natural antimicrobial peptides (AMPs) are promising candidates for developing a generation
of new antimicrobials to meet the challenge of antibiotic-resistant pathogens such as …

Antibiotics play a vital role in saving millions of lives from fatal infections; however, the
inappropriate use of antibiotics has led to the emergence and propagation of drug …

Objectives Staphylococcus aureus survives inside eukaryotic cells. Our objective was to
assess the activity of NZ2114, a novel peptidic antibiotic, against intracellular S. aureus in …

Short antimicrobial peptides with nine and eleven residues were developed against several
clinically important bacterial and fungal pathogens (specifically Escherichia coli …

The increasing resistance of bacteria to conventional antibiotics and the challenges posed
by intracellular bacteria, which may be responsible for chronic and recurrent infections, have …

The emergence of multi-drug resistant bacteria is becoming a major health concern. New
strategies to combat especially Gram-negative pathogens are urgently needed …

Methicillin-resistant Staphylococcus aureus (MRSA) has led to serious infections, especially
in hospitals and clinics, where treatment and prevention have become more difficult due to …

The antipseudomonal efficiency and mechanism of action of a novel engineered
antimicrobial peptide, T9W, were evaluated in this study. T9W displayed high activity, with a …

In recent years, the widespread use of antibiotics has caused many bacterial pathogens
resistance to conventional antibiotics. Therefore, generation of new antibiotics to control and …

The antimicrobial peptide SET-M33 is under study for the development of a new antibiotic
against major Gram-negative pathogens. Here we report the toxicological evaluation of SET …