Isomerization of an antimicrobial peptide broadens antimicrobial spectrum to gram-positive bacterial pathogens

C Falciani, L Lozzi, S Pollini, V Luca, V Carnicelli… - 2012 - journals.plos.org
The branched M33 antimicrobial peptide was previously shown to be very active against
Gram-negative bacterial pathogens, including multidrug-resistant strains. In an attempt to …

Mechanism of action and in vitro activity of short hybrid antimicrobial peptide PV3 against Pseudomonas aeruginosa

H Memariani, D Shahbazzadeh, JM Sabatier… - Biochemical and …, 2016 - Elsevier
Antimicrobial peptides are attractive candidates for developing novel therapeutic agents,
since they are lethal to a broad spectrum of pathogens and have a unique low tendency for …

Clinical applications of amphibian antimicrobial peptides

JM Conlon, A Sonnevend - Hamdan Medical Journal, 2011 - journals.lww.com
Frog skin constitutes a rich source of peptides with broad spectrum antimicrobial activity
against strains of antibioticresistant bacteria and fungi and several hundred such peptides …

A novel antimicrobial peptide with broad-spectrum and exceptional stability derived from the natural peptide Brevicidine

P Yang, W Mao, J Zhang, Y Yang, F Zhang… - European Journal of …, 2024 - Elsevier
The global issue of antibiotic resistance is increasingly severe, highlighting the urgent
necessity for the development of new antibiotics. Brevicidine, a natural cyclic lipopeptide …

Synergistic Effect of Abietic Acid with Oxacillin against Methicillin-Resistant Staphylococcus pseudintermedius

E Buommino, A Vollaro, FP Nocera, F Lembo… - Antibiotics, 2021 - mdpi.com
Resin acids are valued in traditional medicine for their antiseptic properties. Among these,
abietic acid has been reported to be active against methicillin-resistant Staphylococcus …

De novo generation of short antimicrobial peptides with enhanced stability and cell specificity

H Kim, JH Jang, SC Kim, JH Cho - Journal of Antimicrobial …, 2014 - academic.oup.com
Abstract Objectives Though antimicrobial peptides (AMPs) show great potential as novel
antibiotics, therapeutic applications are hindered by their low stability, toxicity and high …

Antimicrobial peptides effectively kill a broad spectrum of Listeria monocytogenes and Staphylococcus aureus strains independently of origin, sub-type, or virulence …

CT Gottlieb, LE Thomsen, H Ingmer, PH Mygind… - BMC microbiology, 2008 - Springer
Abstract Background Host defense peptides (HDPs), or antimicrobial peptides (AMPs), are
important components of the innate immune system that bacterial pathogens must overcome …

A novel short anionic antibacterial peptide isolated from the skin of Xenopus laevis with broad antibacterial activity and inhibitory activity against breast cancer cell

S Li, L Hao, W Bao, P Zhang, D Su, Y Cheng… - Archives of …, 2016 - Springer
A vastarray of bioactive peptides from amphibian skin secretions is attracting increasing
attention due to the growing problem of bacteria resistant to conventional antibiotics. In this …

In vitro activity of novel in silico‐developed antimicrobial peptides against a panel of bacterial pathogens

AA Romani, MC Baroni, S Taddei… - Journal of Peptide …, 2013 - Wiley Online Library
Antimicrobial‐peptide‐based therapies could represent a reliable alternative to overcome
antibiotic resistance, as they offer potential advantages such as rapid microbicidal activity …

Amphipathic peptide antibiotics with potent activity against multidrug-resistant pathogens

J Shi, C Chen, D Wang, Z Tong, Z Wang, Y Liu - Pharmaceutics, 2021 - mdpi.com
The emergence and prevalence of multidrug-resistant (MDR) bacteria have posed a serious
threat to public health. Of particular concern are methicillin-resistant Staphylococcus aureus …