Objectives To examine if therapeutic hypothermia reduces the composite outcome of death,
moderate or severe disability at 18 months or more after mild neonatal encephalopathy …

Importance Hypoxic-ischemic encephalopathy (HIE) occurs in 1 to 8 per 1000 live births in
developed countries. Historically, the clinician has had little to offer neonates with HIE other …

Therapeutic hypothermia holds promise as a rescue neuroprotective strategy for hypoxic-
ischemic injury, but the incidence of severe neurologic sequelae with hypothermia is …

Objective To characterize the implementation of hypothermia for neonatal hypoxic ischemic
encephalopathy (HIE) in a population-based cohort. Study design Using the California …

Hypoxic-ischemic encephalopathy (HIE) is a severe central nervous system injury in
neonates secondary to perinatal asphyxia. It may cause devastating lifelong neurocognitive …

Abstract Purpose of Review Therapeutic hypothermia reduces death or disability in term and
near-term infants with moderate-severe hypoxic-ischemic encephalopathy. Nevertheless …

Therapeutic hypothermia is a standard of care for infants≥ 36 weeks gestational age (GA)
with moderate-to-severe hypoxic-ischemic encephalopathy. Because some studies included …

Objective: Therapeutic hypothermia reduces cerebral injury and improves the neurological
outcome secondary to hypoxic ischemic encephalopathy in newborns. It has been indicated …

Opinion statement Neonatal Hypoxic-ischemic encephalopathy in full term infants has been
associated with a high risk for morbidity and mortality. The patho-physiology of brain injury …

Background We previously reported early results of a randomized trial of whole-body
hypothermia for neonatal hypoxic–ischemic encephalopathy showing a significant reduction …