Whole-body hypothermia for term and near-term newborns with hypoxic-ischemic encephalopathy: a randomized controlled trial

SE Jacobs, CJ Morley, TE Inder… - … of pediatrics & …, 2011 - jamanetwork.com
Objective To determine the effectiveness and safety of moderate whole-body hypothermia in
newborns with hypoxic-ischemic encephalopathy born in hospitals with and without …

Effect of depth and duration of cooling on death or disability at age 18 months among neonates with hypoxic-ischemic encephalopathy: a randomized clinical trial

S Shankaran, AR Laptook, A Pappas, SA McDonald… - Jama, 2017 - jamanetwork.com
Importance Hypothermia for 72 hours at 33.5° C for neonatal hypoxic-ischemic
encephalopathy reduces death or disability, but rates continue to be high. Objective To …

Selective head cooling with mild systemic hypothermia after neonatal hypoxic-ischemic encephalopathy: a multicenter randomized controlled trial in China

W Zhou, G Cheng, X Shao, X Liu, R Shan… - The Journal of …, 2010 - Elsevier
OBJECTIVE: To investigate the efficacy and safety of selective head cooling with mild
systemic hypothermia in hypoxic-ischemic encephalopathy (HIE) in newborn infants. STUDY …

[HTML][HTML] Cognitive outcomes in late childhood and adolescence of neonatal hypoxic-ischemic encephalopathy

BL Lee, HC Glass - Clinical and experimental pediatrics, 2021 - ncbi.nlm.nih.gov
Hypoxic-ischemic encephalopathy (HIE) is the most common cause of neonatal
encephalopathy with a global incidence of approximately 1 to 8 per 1,000 live births …

Evolution of encephalopathy during whole body hypothermia for neonatal hypoxic-ischemic encephalopathy

S Shankaran, AR Laptook, JE Tyson… - The Journal of …, 2012 - Elsevier
OBJECTIVE: To examine the predictive ability of stage of hypoxic-ischemic encephalopathy
(HIE) for death or moderate/severe disability at 18 months among neonates undergoing …

[HTML][HTML] Neonatal hypoxic-ischemic encephalopathy diagnosis and treatment: a National Survey in China

Z Wang, P Zhang, W Zhou, S Xia, W Zhou, X Zhou… - BMC pediatrics, 2021 - Springer
Background Neonatal hypoxic-ischemic encephalopathy (HIE) affects as many as 100,000
infants each year in China. Therapeutic hypothermia reduces HIE related mortality and long …

[HTML][HTML] Assessment of brain tissue injury after moderate hypothermia in neonates with hypoxic–ischaemic encephalopathy: a nested substudy of a randomised …

M Rutherford, LA Ramenghi, AD Edwards… - The Lancet …, 2010 - thelancet.com
Background Moderate hypothermia in neonates with hypoxic–ischaemic encephalopathy
might improve survival and neurological outcomes at up to 18 months of age, although …

[HTML][HTML] Therapeutic hypothermia on neonatal transport: 4-year experience in a single NICU

K Fairchild, D Sokora, J Scott, S Zanelli - Journal of Perinatology, 2010 - nature.com
Objective: Therapeutic hypothermia instituted within 6 h of birth has been shown to improve
neurodevelopmental outcomes in term newborns with moderate–to–severe hypoxic …

Trends in the incidence and management of hypoxic-ischaemic encephalopathy in the therapeutic hypothermia era: a national population study

L Shipley, C Gale, D Sharkey - Archives of Disease in Childhood-Fetal …, 2021 - fn.bmj.com
Objective Hypoxic-ischaemic encephalopathy (HIE) remains a leading cause of neonatal
mortality and neurodisability. We aimed to determine the incidence of HIE and management …

[HTML][HTML] Prognostic value of clinical tests in neonates with hypoxic-ischemic encephalopathy treated with therapeutic hypothermia: a systematic review and meta …

W Liu, Q Yang, H Wei, W Dong, Y Fan, Z Hua - Frontiers in neurology, 2020 - frontiersin.org
Background and Objective: There remains an unmet clinical need for markers that predict
outcomes in the hypothermia-treated (HT) infants with HIE. The aim of this meta-analysis …