NFκB signaling

E O'Dea, A Hoffmann - Wiley Interdisciplinary Reviews …, 2009 - Wiley Online Library
signaling pathways to activate NF-κB, and effect distinct cellular responses. Mathematical
modeling of the NF-κB … -talk regulation of NF-κB. In this review, we discuss the regulation of …

[PDF][PDF] NF-κB signaling pathway and free radical impact

A Siomek - Acta Biochimica Polonica, 2012 - bibliotekanauki.pl
… Reduction/oxidation control of both the cytoplasmic and nuclear steps of NFκB activation
involves IκBs degradation, NF-κB DNA binding, NF-κB transcriptional activity, and chromatin …

NF-κB signaling pathways: role in nervous system physiology and pathology

S Mincheva-Tasheva, RM Soler - The Neuroscientist, 2013 - journals.sagepub.com
… The list of NF-κB functions in the central and peripheral nervous … The present review of the
NF-κB pathway places special … the important role of NF-κB signaling pathway in the regulation …

Mutations in the NF-κB signaling pathway: implications for human disease

G Courtois, TD Gilmore - Oncogene, 2006 - nature.com
NF-κB signaling pathway have been implicated and discusses the molecular mechanisms by
which these alterations in NF-κB signaling … transducers of NF-κB signaling or disrupt NF-κB-…

NFκB pathway: a good signaling paradigm and therapeutic target

V Tergaonkar - The international journal of biochemistry & cell biology, 2006 - Elsevier
… of stimuli can activate NFκB, which in turn … signaling is a major challenge. A thorough
understanding of this would be instrumental in designing pathway specific inhibitors of NFκB for the …

NF-kappaB signaling pathways in neurological inflammation: a mini review

RH Shih, CY Wang, CM Yang - Frontiers in molecular neuroscience, 2015 - frontiersin.org
… All of these target proteins syntheses are mediated through NF-κB-dependent signaling
pathway. NF-κB has been shown to activate more than 500 genes, which are implicated in …

Signaling via the NFκB system

S Mitchell, J Vargas, A Hoffmann - … Reviews: Systems Biology …, 2016 - Wiley Online Library
… The canonical NFκB signaling pathway (aka NEMO-dependent pathway) is mediated by
kinase complexes consisting of the scaffold/adaptor protein NEMO (aka IKKγ) and two IκB …

The noncanonical NFκB pathway

SC Sun - Immunological reviews, 2012 - Wiley Online Library
… factor-κB (NF-κB) signaling pathway mediates activation of the p52/RelB NF-κB complex and,
… The signaling pathways that mediate NF-κB activation can be classified into canonical and …

Posttranslational modifications of NF-κB: another layer of regulation for NF-κB signaling pathway

B Huang, XD Yang, A Lamb, LF Chen - Cellular signalling, 2010 - Elsevier
… regulatory events for the activation of NF-κB are well studied, much less is known about the
nuclear regulation of NF-κB. Emerging evidence suggests that NF-κB undergoes a variety of …

Crosstalk in NF-κB signaling pathways

A Oeckinghaus, MS Hayden, S Ghosh - Nature immunology, 2011 - nature.com
signaling to other pathways. In this review we briefly introduce these important NF-κB signaling
… that allow for both integration and communication with non-NF-κB signaling pathways. …