… and PD-L2 in primary tumor tissue (P < 0.05, Figure 2,B). The score was created … up IRS
values for PD-L1 and PD-L2. Multivariate Cox regression revealed the combined PD-L1 and PD-…

… Thus, the way to regulate PD-L1 expression levels in cancer cells is crucial to exploring …
We further revealed that ITGA2 interacted with STAT3 and up-regulated PD-L1 expression by …

… We showed in the present study that the upregulation of PD-L1 induced by IFN-γ was not
related to … Therefore, it seems likely that IFN-γ signaling to control PD-L1 regulation is mediated …

… and taxane up-regulate PD-L1 expression in some subtypes of triple negative breast cancer
(TNBC) via NF- K B [92]. Next to the transcriptional control of PD-L1 expression, epigenetic …

… PD-1/PD-L1 is currently the predominant strategy and, in this context, PD-L1 is the more
studied protein since its regulation … as an important mechanism regulating PD-L1 expression. …

Oral squamous cell carcinoma (OSCC), which is typically preceded by oral leukoplakia (OL),
is a common malignancy with poor prognosis. However, the signaling molecules governing …

… factor regulating PD-L1 expression in cancer cells, and we suggest that the activation of
Chk1 following DNA end resection is a critical step leading to the upregulation of PD-L1 (Fig. 7). …

… To clarify whether ERK1/2-regulated PD-L1 is dependent on signaling pathway mechanism,
we tested the viability of HCC827 and Beas-2B-EGFR-19del cells treated with ERK1/2 …

… anti-PD-L1 blocking antibody. Further analyses revealed that IFNα regulated PD-L1 expression
… PD-L1 up-regulation. Our findings underline the important roles of p38 and STAT3 in the …

The purpose of this study was to evaluate the prognostic impact of major histocompatibility
complex (MHC) class I expression and programmed death-ligand 1 (PD-L1) expression in …