The crystal structure of the trp repressor/operator complex shows an extensive contact
surface, including 24 direct and 6 solvent-mediated hydrogen bonds to the phosphate …

The crystal structure of trp represser tandemly bound in a 2: 1 complex to a 16-base-pair
palindromic DNA containing a central trp operator half-site has been determined and refined …

ON the basis of the crystal structure of the trp represser/operator complex1, it has been
proposed that the specificity of the interaction can be explained not only by direct hydrogen …

Abstract Comparison of the crystal structure of inactive unliganded trp aporepressor with that
of trp repressor shows that binding tryptophan activates the dimer a thousandfold by moving …

The crystal structure of the Escherichia coli trp repressor has been solved to atomic
resolution. The dimeric protein has a remarkable subunit interface in which five of each …

Oligonucleotide-directed mutagenesis of the codons for glutamine-68 (Gln68), lysine-72
(Lys72), isoleucine-79 (Ile79), alanine-80 (Ala80), and threonine-81 (Thr81) of the …

An orthorhombic crystal form of trp repressor (aporepressor plus L‐tryptophan ligand) was
solved by molecular replacement, refined to 1.65 Å resolution, and compared to the structure …

High resolution crystallographic analysis of the trp repressor‐operator complex indicates
that the principal determinants of specificity are water mediated hydrogen bonds between …

We have determined the solution structures and examined the dynamics of the Escherichia
coli trp repressor (a 25‐kDa dimer), with and without the co‐repressor l‐tryptophan, from …

The solution structures of the complex between Escherichia coli trp holorepressor and a 20
base-pair consensus operator DNA were determined. The majority of proton chemical shifts …