Emerging treatment strategies for acute myeloid leukemia (AML) in the elderly

A Kuendgen, U Germing - Cancer Treatment Reviews, 2009 - Elsevier
Acute myeloid leukemia (AML) is more prevalent in older adults, with an incidence in the
United States of 17.6 per 100,000 for those⩾ 65 years of age, compared with an incidence of …

Acute myeloid leukemia in the elderly: conventional and novel treatment approaches

CM Craig, GJ Schiller - Blood reviews, 2008 - Elsevier
Acute Myeloid Leukemia (AML) is a disorder affecting primarily elderly individuals and
poses significant treatment challenges. Much has been learned about the underlying …

Alternative novel therapies for the treatment of elderly acute myeloid leukemia patients

A Isidori, A Venditti, L Maurillo… - Expert Review of …, 2013 - Taylor & Francis
With a median age at diagnosis of approximately 65–70 years, acute myeloid leukemia
(AML) represents a major therapeutic challenge in the elderly. Only 30–35% of elderly …

Treatment of acute myeloid leukemia in older adults

A Alsouqi, E Geramita, A Im - Cancers, 2023 - mdpi.com
Simple Summary In this review article, we describe the landscape of available treatments for
older and medically unfit patients with AML. We review the historical practice of AML …

Non-intensive acute myeloid leukemia therapies for older patients

R Babakhanlou, F Ravandi-Kashani - Expert review of hematology, 2023 - Taylor & Francis
Introduction Acute myeloid leukemia (AML) is an aggressive disease predominantly
affecting the elderly population. The elderly population represents a challenging group to …

Treating acute myeloid leukemia in older adults

ES Wang - Hematology 2014, the American Society of …, 2014 - ashpublications.org
Acute myeloid leukemia (AML) is a disease of older adults, with a median age of 67 years at
presentation. In the past, only a third of older patients (defined as individuals older than 60 …

Shifting paradigms in the treatment of older adults with AML

TW LeBlanc, HP Erba - Seminars in Hematology, 2019 - Elsevier
The treatment of acute myeloid leukemia has been associated with dismal outcomes despite
available therapies. The morbidity and mortality associated with acute myeloid leukemia …

New treatment options for older patients with acute myeloid leukemia

K Saxena, M Konopleva - Current treatment options in oncology, 2021 - Springer
Opinion statement The treatment of acute myeloid leukemia (AML) has evolved considerably
over the past several years. Advances in the field have historically benefited younger …

Treatment of acute myeloid leukemia: are we making progress?

AK Burnett - Hematology 2010, the American Society of …, 2012 - ashpublications.org
With a few subgroups as exceptions, such as younger patients with more favorable genetic
disease, improvement in the treatment of acute myeloid leukemia has been slow. There is a …

Acute myeloid leukemia in older adults

M Yanada, T Naoe - International journal of hematology, 2012 - Springer
Acute myeloid leukemia (AML) is predominantly a disease of older adults, with a median
age at diagnosis of over 65 years. AML in older adults differs biologically and clinically from …