The need for third-line treatment in non-small cell lung cancer: an overview of new options

KN Syrigos, MW Saif, EM Karapanagiotou… - Anticancer …, 2011 - ar.iiarjournals.org
… that compared pemetrexed to docetaxel as second-line treatment… and efficacy of erlotinib
as second and third line treatment in … the efficacy of erlotinib or gefitinib when compared to …

Erlotinib or best supportive care for third-line treatment of advanced non-small-cell lung cancer: a real-world cost-effectiveness analysis

I Cromwell, K van der Hoek, SCM Taylor, B Melosky… - Lung Cancer, 2012 - Elsevier
… the efficacy of a treatment, they are insufficient to establish the … (CE) of the third-line erlotinib
protocol, compared to the next-… Lee compared second-line gefitinib (trade name Iressa™, …

[HTML][HTML] Second-line treatment of advanced non-small cell lung cancer

C Gridelli, A Ardizzoni, F Ciardiello, N Hanna… - Journal of Thoracic …, 2008 - Elsevier
… Docetaxel has demonstrated superiority compared with best … to chemotherapy, and in all
patients as third-line treatment after … activity and efficacy of treatment with erlotinib and gefitinib. …

[HTML][HTML] Anlotinib as a third-line therapy in patients with refractory advanced non-small-cell lung cancer: a multicentre, randomised phase II trial (ALTER0302)

B Han, K Li, Y Zhao, B Li, Y Cheng, J Zhou, Y Lu… - … journal of cancer, 2018 - nature.com
… and efficacy of third-line anlotinib for patients with refractory … erlotinib or gefitinib and have
a PS of 0–3, the efficacy of this … in NSCLC, although direct comparisons of AEs with other …

Phase II study of erlotinib as third-line monotherapy in patients with advanced non-small-cell lung cancer without epidermal growth factor receptor mutations

S Matsuura, N Inui, Y Ozawa… - Japanese Journal of …, 2011 - academic.oup.com
… the efficacy and safety of erlotinib monotherapy as third-line … of its equivalent efficacy and
lower toxicity compared with … active dose than gefitinib may induce different efficacy in patients …

[HTML][HTML] Comparative efficacy and safety of second-line treatments for advanced non-small cell lung cancer with wild-type or unknown status for epidermal growth …

P Créquit, A Chaimani, A Yavchitz, N Attiche… - BMC medicine, 2017 - Springer
… Docetaxel, pemetrexed, erlotinib, and gefitinib are … In this paper, we present an NMA
comparing the relative efficacy … including both second- and third-line therapy, because there is no …

[HTML][HTML] … impact of previous therapy strategy on the efficiency of anlotinib hydrochloride as a third-line treatment on patients with advanced non-small cell lung cancer  …

L Wang, Z He, S Yang, H Tang, Y Wu, S Li… - … Lung Cancer …, 2019 - ncbi.nlm.nih.gov
… the gefitinib (P=0.008), erlotinib, icotinib, and only OS in gefitinib … the OS times of patients
compared to placebo. However, the … treatments had no impact on the efficacy of anlotinib in …

… placebo for patients with advanced, metastatic non-small-cell lung cancer after failure of erlotinib, gefitinib, or both, and one or two lines of chemotherapy (LUX-Lung 1 …

VA Miller, V Hirsh, J Cadranel, YM Chen, K Park… - The lancet …, 2012 - thelancet.com
… We aimed to assess its efficacy in patients with advanced lung adenocarcinoma with … This
study, in the third-line and fourth-line setting, failed to show a difference between groups in its …

[HTML][HTML] Second and third line treatment in advanced non-small cell lung cancer

AG Favaretto, C Magro - Discovery Medicine, 2009 - discoverymedicine.com
chemotherapy has shown no advantage as compared to single … efficacy of combinations
among chemotherapy and targeted … Erlotinib 150 mg/day is now used as third line treatment of …

Erlotinib, docetaxel, and gefitinib in sequential cohorts with relapsed non-small cell lung cancer

S Popat, Y Barbachano, S Ashley, A Norton, M O'Brien - Lung Cancer, 2008 - Elsevier
… of erlotinib (E) and gefitinib (G) in patients with relapsed NSCLC in both second- and third-line
settings, and compared this … [3] and JMEI [5] studies suggest that efficacy may be similar. …