An engineered VEGF‐activating zinc finger protein transcription factor improves blood flow and limb salvage in advanced‐age mice
… In Cys-2 His-2 ZFPs, represented by the mouse transcription … nonreplicative, recombinant
adenovirus vector was generated (… To determine the effects of Ad-MVZ+426b gene delivery on …
adenovirus vector was generated (… To determine the effects of Ad-MVZ+426b gene delivery on …
Localization of vascular response to VEGF is not dependent on heparin binding
ML Springer, A Banfi, J Ye, G von Degenfeld… - The FASEB …, 2007 - Wiley Online Library
… the effects of their delivery to skeletal muscle because this is one of the main target tissues for
gene … We have previously described a VEGF gene delivery system in which primary mouse …
gene … We have previously described a VEGF gene delivery system in which primary mouse …
Adenovirus-mediated gene transfer to normal and atherosclerotic arteries: a novel approach
CD Ríos, H Ooboshi, D Piegors… - … , and vascular biology, 1995 - Am Heart Assoc
… Recently, several investigators have demonstrated that delivery of adenovirus vector by a …
after intraluminal delivery. These limitations led us to seek an alternative method for delivery of …
after intraluminal delivery. These limitations led us to seek an alternative method for delivery of …
Gene therapy for trigeminal pain in mice
AZ Tzabazis, M Klukinov, DP Feliciano, SP Wilson… - Gene therapy, 2014 - nature.com
… It has been shown that different mouse strains show different … The cranium and underlying
brain tissue were removed and … Adenovector GAD65 gene delivery into the rat trigeminal …
brain tissue were removed and … Adenovector GAD65 gene delivery into the rat trigeminal …
The menace of severe adverse events and deaths associated with viral gene therapy and its potential solution
A Kachanov, A Kostyusheva, S Brezgin… - Medicinal Research …, 2024 - Wiley Online Library
… and improve delivery of DNA into specific tissues or cell types, … utilize AAV as the gene
delivery platform, this review will … -CB-CFTR, an adenovirus vector containing the cystic fibrosis …
delivery platform, this review will … -CB-CFTR, an adenovirus vector containing the cystic fibrosis …
Targeting the cell cycle machinery for the treatment of cardiovascular disease
KA Bicknell, EL Surry, G Brooks - … pharmacy and pharmacology, 2003 - Wiley Online Library
… delivery methods that are available for introducing DNA and … recombinant adenovirus vector
decreased endothelial cell … the aortic tissue into the surrounding area in a tissue culture dish…
decreased endothelial cell … the aortic tissue into the surrounding area in a tissue culture dish…
Journey of mesenchymal stem cells for homing: strategies to enhance efficacy and safety of stem cell therapy
SK Kang, IS Shin, MS Ko, JY Jo… - Stem cells …, 2012 - Wiley Online Library
… After intravenous delivery, MSCs are found at low or very low … “arrest of MSCs within the
vasculature of the respective tissue,” … on MSCs using an adenovirus vector resulted in successful …
vasculature of the respective tissue,” … on MSCs using an adenovirus vector resulted in successful …
[HTML][HTML] Immunity against heterosubtypic influenza virus induced by adenovirus and MVA expressing nucleoprotein and matrix protein-1
T Lambe, JB Carey, Y Li, AJ Spencer… - Scientific reports, 2013 - nature.com
… –155 ) in the BALB/c mouse strain that was studied is completely … virus challenge following
intranasal delivery 9 . Intranasal … can induce differential expression of tissue-selective homing …
intranasal delivery 9 . Intranasal … can induce differential expression of tissue-selective homing …
Molecular imaging of nuclear factor-Y transcriptional activity maps proliferation sites in live animals
F Goeman, I Manni, S Artuso… - Molecular biology of …, 2012 - Am Soc Cell Biol
… The transgenic mouse model we have developed harbors a strictly NF-Y–… verify tissue
distribution of luciferase, we measured enzymatic activity in homogenates of 21 different tissues …
distribution of luciferase, we measured enzymatic activity in homogenates of 21 different tissues …
[HTML][HTML] Development of novel adenoviral vectors to overcome challenges observed with HAdV-5–based constructs
Recombinant vectors based on human adenovirus serotype 5 (HAdV-5) have been extensively
studied in preclinical models and clinical trials over the past two decades. However, the …
studied in preclinical models and clinical trials over the past two decades. However, the …