… two types - embryonic stem cells (ESCs) and adult stem cells (… Culturing hESCs in the
presence of actin disrupting agents … known as contact guidance, which is crucial in embryonic …

… changes (contact guidance) in cellular, cytoskeletal, and … and modulate stem cell differentiation
into a specific lineage. … II), and cytochalasin D (actin disrupting agent) could be employed. …

… cellular functions.95,140 It is made of globular actin (G-actin), … either the LINC complex was
disrupted or a loss of lamins … contact guidance, have confirmed that a variety of tissue cells, …

… To further address this possibility, we evaluated the effect of … polymerization and therefore
reduces contractility of the actin … Treatment of the cells with cytoskeletal-disrupting agents gave …

… a reduced cell spreading morphology with diffuse actin and less … width, the cells preferred
to follow contact guidance and the … , discrete, isotropic nanopillars tend to disrupt the formation …

… Actin is used as protein loading control. RPE (bottom lane) … three cells deep, and the inner
retina lamination was not disrupted. … (arrows) formed a layer closely contact with the host RPE …

… We explore how engineered materials target cytoskeletal remodeling and guide … contact
expansion that determines the anchoring strength of actin to E-cadherins in individual cells, …

… into specific lineages can address this issue. Furthermore, the … proliferation of human embryonic
stem cells through cytoskeletal-… by the effect of actin-disrupting agents. Alternatively, the …

… Stem cells, such as embryonic stem cells (ESCs), induced … cytoskeleton by the addition
of the actin-disrupting agent … study the effect of cell–cell contact between stem cells on cell …

… effect in a variety of cardiac preparations, did not affect the [Ca … and a negative inotropic
agent, did not affect the [Ca 2+ ] i … , it is important to address the apparent discrepancy between …