[HTML][HTML] Effect of 1-palmitoyl-2-linoleoyl-3-acetyl-rac-glycerol on Immune Functions in Healthy Adults in a Randomized Controlled Trial

HJ Hwang, KY Sohn, YH Han, S Chong… - Immune …, 2015 - synapse.koreamed.org
… Synthesis of EC-18 Pure 1-palmitoyl-3-acetyl-rac-glycerol is a key interme… 1-palmitoyl-rac-glycerol
and acetylchloride as starting materials. And resulting crude 1-palmitoyl-3-acetyl-rac-…

Toxicity of rac-1 (3)-palmitoyl glycerol in weanling mice

R Schnitzer-Polokoff, SB Tove - The Journal of Nutrition, 1979 - Elsevier
… the rac-l(3)-palmitoyl glycerol is acetylated the … acetylation of the two open hydroxyl
groups. Prior to this experiment, we tested the effect of acetyla tion on the toxicity of rac-1(3)-palmitoyl

[HTML][HTML] 1-palmitoyl-2-linoleoyl-3-acetyl-rac-glycerol (EC-18) Modulates Th2 Immunity through Attenuation of IL-4 Expression

SY Yoon, HB Kang, YE Ko, SH Shin, YJ Kim… - Immune …, 2015 - synapse.koreamed.org
… In this study, we have tried to elucidate the function of 1-palmitoyl-2-linoleoyl-3-acetyl-rac-glycerol
(EC-18) as an essential modulator of Th1/ Th2 balance. EC-18 has showed an …

[HTML][HTML] 1-palmitoyl-2-linoleoyl-3-acetyl-rac-glycerol ameliorates arthritic joints through reducing neutrophil infiltration mediated by IL-6/STAT3 and MIP-2 activation

YJ Kim, JM Shin, SH Shin, JH Kim, KY Sohn, HJ Kim… - Oncotarget, 2017 - ncbi.nlm.nih.gov
… In this study, we show that 1-palmitoyl-2-linoleoyl-3-acetyl-rac-glycerol (PLAG) decreases
neutrophil migration by regulating the activity of STAT3, a regulator of IL-6 and MIP-2 …

1palmitoyl‐2‐linoleoyl‐3‐acetylrac‐glycerol (PLAG) reduces hepatic injury in concanavalin A‐treated mice

YE Ko, SY Yoon, SY Ly, JH Kim… - Journal of Cellular …, 2018 - Wiley Online Library
Abstract 1palmitoyl‐2‐linoleoyl‐3‐acetylrac‐glycerol (PLAG), a chemically synthesized
monoacetyldiaglyceride, is one of the constituents in Sika deer antlers and has been known …

[HTML][HTML] 1Palmitoyl‑2‑linoleoyl‑3‑acetylrac‑glycerol ameliorates EGF‑induced MMP‑9 expression by promoting receptor desensitization in MDA‑MB‑231 cells

KH Yang, GT Kim, S Choi, SY Yoon… - Oncology …, 2020 - spandidos-publications.com
… the effects of 1palmitoyl‑2‑linoleoyl‑3‑acetylrac‑glycerol (… activity of transcription factor
AP‑1 using a luciferase assay. PLAG … This faster intracellular EGFR degradation reduced AP‑1‑…

[HTML][HTML] 1-Palmitoyl-2-Linoleoyl-3-Acetyl-rac-Glycerol (PLAG) rapidly resolves LPS-induced acute lung injury through the effective control of neutrophil recruitment

HR Lee, SH Shin, JH Kim, KY Sohn, SY Yoon… - Frontiers in …, 2019 - frontiersin.org
Acute lung injury (ALI) is an acute respiratory failure that is associated with excessive
neutrophil recruitment and high mortality. To assess the efficacy of 1-palmitoyl-2-linoleoyl-3-acetyl-…

1Palmitoyl‐2‐linoleoyl‐3‐acetylrac‐glycerol ameliorates chemoradiation‐induced oral mucositis

S Choi, SH Shin, HR Lee, KY Sohn, SY Yoon… - Oral …, 2020 - Wiley Online Library
Objective This study was designed to investigate whether necroptosis is involved in the
pathogenesis of chemoradiation‐induced oral mucositis in a murine model and whether 1‐…

[HTML][HTML] 1-Palmitoyl-2-linoleoyl-3-acetyl-rac-glycerol (PLAG) attenuates gemcitabine-induced neutrophil extravasation

J Jeong, YJ Kim, DY Lee, BG Moon, KY Sohn… - Cell & Bioscience, 2019 - Springer
… , L-selectin and LFA-1. Inhibition of CXCR2 by its antagonist, … also demonstrated that 1-palmitoyl-2-linoleic-3-hydroxyl-rac-…
migration, suggesting that an acetyl group at the third position …

Quantification of EC-18, a synthetic monoacetyldiglyceride (1-palmitoyl-2-linoleoyl-3-acetyl-rac-glycerol), in rat and mouse plasma by liquid-chromatography/tandem …

HM Ryu, YS Jeong, CS Yim, JH Lee… - Journal of Pharmaceutical …, 2017 - Elsevier
EC-18 (ie, 1-palmitoyl-2-linoleoyl-3-acetyl-rac-glycerol), an active ingredient in Rockpid ® ,
has been reported to be useful in controlling various types of inflammations, particularly …