[HTML][HTML] Effect of 1-palmitoyl-2-linoleoyl-3-acetyl-rac-glycerol on Immune Functions in Healthy Adults in a Randomized Controlled Trial

HJ Hwang, KY Sohn, YH Han, S Chong… - Immune …, 2015 - synapse.koreamed.org
We previously reported that 1-palmitoyl-2-linoleoyl-3-acetyl-rac-glycerol (PLAG) accelerates
hematopoiesis and has an improving effect on animal disease models such as sepsis and …

[HTML][HTML] 1-palmitoyl-2-linoleoyl-3-acetyl-rac-glycerol ameliorates arthritic joints through reducing neutrophil infiltration mediated by IL-6/STAT3 and MIP-2 activation

YJ Kim, JM Shin, SH Shin, JH Kim, KY Sohn, HJ Kim… - Oncotarget, 2017 - ncbi.nlm.nih.gov
… In this study, we show that 1-palmitoyl-2-linoleoyl-3-acetyl-rac-glycerol (PLAG) decreases
neutrophil migration by regulating the activity of STAT3, a regulator of IL-6 and MIP-2

[HTML][HTML] 1-palmitoyl-2-linoleoyl-3-acetyl-rac-glycerol (EC-18) Modulates Th2 Immunity through Attenuation of IL-4 Expression

SY Yoon, HB Kang, YE Ko, SH Shin, YJ Kim… - Immune …, 2015 - synapse.koreamed.org
… In this study, we have tried to elucidate the function of 1-palmitoyl-2-linoleoyl-3-acetyl-rac-glycerol
(EC-18) as an essential modulator of Th1/ Th2 balance. EC-18 has showed an …

1‐palmitoyl‐2linoleoyl‐3‐acetylrac‐glycerol (PLAG) reduces hepatic injury in concanavalin A‐treated mice

YE Ko, SY Yoon, SY Ly, JH Kim… - Journal of Cellular …, 2018 - Wiley Online Library
palmitoyl‐2linoleoyl‐3‐acetylrac‐glycerol (PLAG), a chemically synthesized
monoacetyldiaglyceride, is one of the constituents in Sika deer antlers and has been known …

[HTML][HTML] 1-Palmitoyl-2-Linoleoyl-3-Acetyl-rac-Glycerol (PLAG) rapidly resolves LPS-induced acute lung injury through the effective control of neutrophil recruitment

HR Lee, SH Shin, JH Kim, KY Sohn, SY Yoon… - Frontiers in …, 2019 - frontiersin.org
Acute lung injury (ALI) is an acute respiratory failure that is associated with excessive
neutrophil recruitment and high mortality. To assess the efficacy of 1-palmitoyl-2-linoleoyl-3-acetyl-…

[HTML][HTML] PLAG (1-Palmitoyl-2-Linoleoyl-3-Acetyl-rac-Glycerol) modulates eosinophil chemotaxis by regulating CCL26 expression from epithelial cells

J Jeong, YJ Kim, SY Yoon, YJ Kim, JH Kim, KY Sohn… - PLoS …, 2016 - journals.plos.org
Increased number of eosinophils in the circulation and sputum is associated with the severity
of asthma. The respiratory epithelium produces chemokine (CC motif) ligands (CCL) which …

1‐Palmitoyl‐2linoleoyl‐3‐acetylrac‐glycerol ameliorates chemoradiation‐induced oral mucositis

S Choi, SH Shin, HR Lee, KY Sohn, SY Yoon… - Oral …, 2020 - Wiley Online Library
Objective This study was designed to investigate whether necroptosis is involved in the
pathogenesis of chemoradiation‐induced oral mucositis in a murine model and whether 1‐…

[HTML][HTML] 1‑Palmitoyl‑2linoleoyl‑3‑acetylrac‑glycerol ameliorates EGF‑induced MMP‑9 expression by promoting receptor desensitization in MDA‑MB‑231 cells

KH Yang, GT Kim, S Choi, SY Yoon… - Oncology …, 2020 - spandidos-publications.com
Activated epidermal growth factor receptors (EGFRs) are crucial for inducing metastasis in
cancer cells by promoting matrix metalloproteinase (MMP) expression. The present study was …

1-Palmitoyl-2-Linoleoyl-3-Acetyl-rac-Glycerol Attenuates Streptozotocin-Induced Pancreatic Beta Cell Damage by Promoting Glucose Transporter 2 Endocytosis

J Kim, JH Kim, KY Sohn, SY Yoon… - Molecular and Cellular …, 2019 - Taylor & Francis
Streptozotocin (STZ) is widely used to induce diabetic rodent models. It is specifically toxic
to pancreatic beta cells and causes severe destruction and dysfunction. We investigated the …

Triacylglycerol, 1-Palmitoyl-2-Linoleoyl-3-Acetyl-rac -Glycerol Isolated from Bovine Udder and its Synthetic Enantiomer can Potentiate the Mitogenic Activity for Mouse …

J Suh, J Kwon, J Eun, Y Lee, J Limb, S Ko… - Cellular Physiology and …, 2003 - karger.com
A factor stimulating a mitogenic activity of peritoneal macrophages is purified from bovine
udder. It is identified as a triglyceride, 1-palmitoyl-2-linoleoyl-3-acetyl-rac -glycerol (rac -MADG)…