… carriers on 1-palmitoyl-2-linoleoyl-3-acetyl-rac-glycerol-loaded solid self-emulsifying drug delivery system: Physicochemical characterization and bioavailability in rats
DS Kim, ES Yang, CS Yong, YS Youn, KT Oh… - Colloids and Surfaces B …, 2017 - Elsevier
… properties and oral bioavailability of 1-palmitoyl-2-linoleoyl-3-acetyl-rac-glycerol (PLAG)-…
studies in rats were performed compared with drug alone. Three solid SEDDSs composed of …
studies in rats were performed compared with drug alone. Three solid SEDDSs composed of …
… -3-acetyl-rac-glycerol-loaded self-emulsifying granule and solid self-nanoemulsifying drug delivery system: powder property, dissolution and oral bioavailability
… property, dissolution and bioavailability of 1-palmitoyl-2-linoleoyl-3-acetyl-rac-glycerol (PLAG…
the oral bioavailability studies were conducted in rats to determine the oral bioavailability of …
the oral bioavailability studies were conducted in rats to determine the oral bioavailability of …
Quantification of EC-18, a synthetic monoacetyldiglyceride (1-palmitoyl-2-linoleoyl-3-acetyl-rac-glycerol), in rat and mouse plasma by liquid-chromatography/tandem …
HM Ryu, YS Jeong, CS Yim, JH Lee… - Journal of Pharmaceutical …, 2017 - Elsevier
… rat and mouse plasma and to evaluate the applicability of the assay in pharmacokinetic studies.
EC-18 was extracted with MeOH from rat … /kg in rats and at 5 mg/kg in mice, respectively, …
EC-18 was extracted with MeOH from rat … /kg in rats and at 5 mg/kg in mice, respectively, …
A novel solid self-nanoemulsifying drug delivery system (S-SNEDDS) for improved stability and oral bioavailability of an oily drug, 1-palmitoyl-2-linoleoyl-3-acetyl-rac …
… 200 mg/kg of PLAG were orally administered to the rats, respectively. Blood samples were
collected from the right femoral artery after 0.05, 0.125, 0.25, 0.5, 1, 2, 3, 4, 6, and 8 h. Plasma …
collected from the right femoral artery after 0.05, 0.125, 0.25, 0.5, 1, 2, 3, 4, 6, and 8 h. Plasma …
[PDF][PDF] preclinical pharmacokinetics and bioavailability studies of S-carboxymethylcysteine, N-acetylcysteine and (-)-carbodine
L Shen - 2008 - getd.libs.uga.edu
… dissertation, bioavailability studies were performed for S-carboxymethylcysteine and Nacetylcysteine, …
affect the bioavailability of ferric pyrophosphate in rats. Amer Soci Nutri Sci J. Nutr. …
affect the bioavailability of ferric pyrophosphate in rats. Amer Soci Nutri Sci J. Nutr. …
[HTML][HTML] Effects of food intake on the relative bioavailability of amifampridine phosphate salt in healthy adults
PE Haroldsen, DG Musson, B Hanson, A Quartel… - Clinical Therapeutics, 2015 - Elsevier
… This study assessed the effect of food on the relative bioavailability of amifampridine in …
and an inactive 3-N-acetyl metabolite were determined. The relative bioavailability values of …
and an inactive 3-N-acetyl metabolite were determined. The relative bioavailability values of …
Dose-related kinetics of aspirin: presystemic acetylation of platelet cyclooxygenase
AK Pedersen, GA FitzGerald - New England Journal of Medicine, 1984 - Mass Medical Soc
… tested the hypothesis that the systemic bioavailability of orally administered aspirin might vary
… Repeated administration of a dose that was poorly bioavailable would result in cumulative …
… Repeated administration of a dose that was poorly bioavailable would result in cumulative …
Resveratrol inhibition of Rac1-derived reactive oxygen species by AMPK decreases blood pressure in a fructose-induced rat model of hypertension
… bioavailability is oxidative stress 34,35 . Oxidative stress can be defined as increased
bioactivity of ROS relative to antioxidant defenses 36 . Oxidative stress reduces NO bioavailability …
bioactivity of ROS relative to antioxidant defenses 36 . Oxidative stress reduces NO bioavailability …
Systematic Review of Human and Animal Studies Examining the Efficacy and Safety of N-Acetylcysteine (NAC) and N-Acetylcysteine Amide (NACA) in Traumatic …
J Bhatti, B Nascimento, U Akhtar, SG Rhind… - Frontiers in …, 2018 - frontiersin.org
… in increased central nervous system bioavailability (31). However, … addressed in a study with
Wistar rats (49) and reported a … individuals regardless of age, sex, or race worldwide. Phase …
Wistar rats (49) and reported a … individuals regardless of age, sex, or race worldwide. Phase …
AZD0284, a potent, selective, and orally bioavailable inverse agonist of retinoic acid receptor-related orphan receptor C2
… Intrinsic permeability improved 3- to 4-fold with respect to 2, although efflux remained high.
A single oral dose of 1 mg/kg administered to Han Wistar rats showed high oral bioavailability …
A single oral dose of 1 mg/kg administered to Han Wistar rats showed high oral bioavailability …
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