… solid self-nanoemulsifying drug delivery system (S-SNEDDS) for improved stability and oral bioavailability of an oily drug, 1-palmitoyl-2-linoleoyl-3-acetyl-rac-glycerol

KS Kim, ES Yang, DS Kim, DW Kim, HH Yoo… - Drug …, 2017 - Taylor & Francis
… a powerful oral drug delivery system for an oily drug, PLAG. … is still unsatisfactory, because
an oily drug hardly dissolves in the … of an oily drug to a practical solid pharmaceutical product. …

[HTML][HTML] Comparison of 1-palmitoyl-2-linoleoyl-3-acetyl-rac-glycerol-loaded self-emulsifying granule and solid self-nanoemulsifying drug delivery system: powder …

DS Kim, JS Kim, SJ Lim, JO Kim, CS Yong, HG Choi… - Pharmaceutics, 2019 - mdpi.com
… The flow ability and bioavailability of oily drugs such as PLAG can be greatly improved by
formulation into SEGS using fluid bed granulation. The conventional solid self-emulsifying …

Effect of inorganic mesoporous carriers on 1-palmitoyl-2-linoleoyl-3-acetyl-rac-glycerol-loaded solid self-emulsifying drug delivery system: Physicochemical …

DS Kim, ES Yang, CS Yong, YS Youn, KT Oh… - Colloids and Surfaces B …, 2017 - Elsevier
… 1-Palmitoyl-2-Linoleoyl-3-Acetyl-rac-Glycerol (PLAG) is a chemically synthesized … pulmonary
disease and asthma [3]; however, PLAG, an oily liquid drug possesses the poorly water-…

Degradation kinetics study of 1-palmitoyl-2-linoleoyl-3-acetyl-rac-glycerol (PLAG) by a validated stability-indicating RP-HPLC method

KS Kim, ES Yang, DS Kim, DW Kim, CS Yong… - … of Pharmaceutical and …, 2018 - Elsevier
… Moreover, PLAG is an oily drug which is poorly water-soluble. However, it is freely soluble
in acetonitrile and alcohol [16], [17]. Different mobile phase proportions of acetonitrile: …

Crystallization and Polymorphism of 1,3-Acyl-Palmitoyl-rac-Glycerols

RJ Craven, RW Lencki - Journal of the American Oil Chemists' Society, 2011 - Springer
… of natural fats and oils (eg palm oil, milk fat) and are known to … of specific structured lipids
and pharmaceutical products [5]. In … 1,3-DAG were prepared by mixing glycerol with a fatty acid …

Glycerol and its derivatives as potential C-3 bio-based building blocks for accessing active pharmaceutical ingredients

R Morodo, L Bovy, DV Silva-Brenes, JCM Monbaliu - Green Chemistry, 2024 - pubs.rsc.org
… of renewable glycerol and its derivatives for the preparation of active pharmaceutical … it
being a by-product of the biodiesel, soap, and cooking oil recycling industries. Most of the …

[HTML][HTML] Effect of 1-palmitoyl-2-linoleoyl-3-acetyl-rac-glycerol on Immune Functions in Healthy Adults in a Randomized Controlled Trial

HJ Hwang, KY Sohn, YH Han, S Chong… - Immune …, 2015 - synapse.koreamed.org
… transfused within 30 days, 8) have taken a medication for the inducer or suppressor of drug
metabolizing … Soybean oil was used as a control to PLAG in this study. Generally, soybean …

… . Part 2. 1 Lipase-catalysed synthesis of 1-O-lauroyl-rac-glycero-3-O-(N α-acetyl-L-amino acid) and 1, 2-di-O-lauroyl-rac-glycero-3-O-(N α-acetyl-L-amino acid) …

C Morán, MR Infante, P Clapés - Journal of the Chemical Society …, 2002 - pubs.rsc.org
… therapeutic interest and as adjuvants for drug and gene delivery (ie, … glycerol]. In the second
step the enzymatic acylation of the hydroxy groups of the amino acid glyceryl ester by fatty

Quantification of EC-18, a synthetic monoacetyldiglyceride (1-palmitoyl-2-linoleoyl-3-acetyl-rac-glycerol), in rat and mouse plasma by liquid-chromatography/tandem …

HM Ryu, YS Jeong, CS Yim, JH Lee… - Journal of Pharmaceutical …, 2017 - Elsevier
EC-18 (ie, 1-palmitoyl-2-linoleoyl-3-acetyl-rac-glycerol), an active ingredient in Rockpid ® ,
has been reported to be useful in controlling various types of inflammations, particularly …

Aqueous self-assembly and physicochemical properties of 1, 2-dilauroyl-rac-glycero-3-(Nα-acetyl-l-arginine)

C Moran, MR Infante, L Pérez, A Pinazo… - Colloids and Surfaces A …, 2008 - Elsevier
glycerol backbone, making it possible to obtain both possible regioisomers: 1,2-di-lauroyl-…
-glycero-3-phosphatidylcholine), a compound characterized by the same length of the fatty, the …