… of the axon–myelin unit in the CNS, and the molecular mechanism by which axonal signals
control myelination, … Thus, abnormal myelin turnover and the failure to degrade inflammatory …

… that injury represents myelin or axonal damage is unclear. The objective was to examine
myelin and axonal changes in patients with newly diagnosed OSA over control subjects. …

… Myelin is a multilamellar cell membrane around axons and is essential for fast saltatory …
of axonal integrity and survival. Congenital and acquired abnormalities of myelin lead to …

… Moreover, oligodendrocytes support axonal integrity and function independent of myelination
per se (for details see main text). Astrocytes (blue) not only contact blood vessels but …

… myelin thickness and preserve axon integrity. In contrast, PTEN is dispensable during myelin
… We demonstrated myelin sheath abnormalities as early as 4 months of age and severe …

… abnormalities, underscoring the importance of peroxisomes in nervous tissue. The
interrelationship between metabolic abnormalities, … for the preservation of axonal integrity and for …

… maintenance of axon-myelin units is disturbed, resulting in both axon and myelin degeneration.
… These examples of myelin abnormality show that disintegration of myelin per se does not …

… integrity in young adults. We hypothesized that childhood lead exposure would alter adult
white matter architecture via deficits in axonal integrity and myelin … diffusion abnormalities in …

… COX inhibitors 5 , post-myelination oligodendrocytes survive well in the absence … myelinated
axons can use lactate when energy-deprived 6 , our findings suggest a model in which axon…

… axonal integrity and neuronal survival are maintained by oligodendrocytes and loss of
this well-coordinated axon… decline associated with myelin abnormalities in the aging brain. …