Guiding empirical antibiotic therapy in orthopaedics: the microbiology of prosthetic joint infection managed by debridement, irrigation and prosthesis retention

E Moran, S Masters, AR Berendt, P McLardy-Smith… - Journal of Infection, 2007 - Elsevier
OBJECTIVES: This study describes the microbiological spectrum of prosthetic joint infection
(PJI) managed by debridement, washout and retention and so guides the choice of empirical …

[HTML][HTML] Early prosthetic joint infection: outcomes with debridement and implant retention followed by antibiotic therapy

J Cobo, LG San Miguel, G Euba, D Rodríguez… - Clinical Microbiology …, 2011 - Elsevier
… When to stop antimicrobial therapy in patients with DAIR and … use antibiotic therapy for several
weeks after debridement … suppressive antimicrobial therapy after debridement, regardless …

Current concepts in debridement: science and strategies

EL Anghel, MV DeFazio, JC Barker… - Plastic and …, 2016 - journals.lww.com
debridement may warrant extended antibiotic therapy and may delay closure. The appropriate
antibiotic … manage the complications of prolonged antibiotic therapy. Further studies are …

Periodontal debridement: still the treatment of choice

CL Drisko - Journal of Evidence Based Dental Practice, 2014 - Elsevier
… , but scarce data is available to determine the long term effects of systemic antibiotic use with
PD or surgery beyond 3–12 months. It is hard to trump a thorough periodontal debridement. …

Efficacy of debridement, antibiotic therapy and implant retention within three months during postoperative instrumented spine infections

H Wille, FA Dauchy, A Desclaux, H Dutronc… - Infectious …, 2017 - Taylor & Francis
… a strategy based on debridement-irrigation and antibiotic therapy achieved cure in 82.2%
of cases after a first debridement-irrigation and in 93.8% after a second debridement-irrigation. …

One hundred and twelve infected arthroplasties treated with 'DAIR'(debridement, antibiotics and implant retention): antibiotic duration and outcome

I Byren, P Bejon, BL Atkins, B Angus… - Journal of …, 2009 - academic.oup.com
… of subjects taking oral antibiotics, on stopping antibiotics and (as a control for the effect of
time elapsed) at day 500 after debridement without reference to antibiotic therapy. We used the …

[HTML][HTML] Changing perioperative prophylaxis during antibiotic therapy and iterative debridement for orthopedic infections?

L Wuarin, M Abbas, S Harbarth, F Waibel, D Holy… - PLoS …, 2019 - journals.plos.org
… iterative debridement were already under systemic antibiotic administration, we could not
determine the impact of iterative surgeries alone (without concomitant antibiotic therapies) on …

[HTML][HTML] Antibiotic therapy duration for prosthetic joint infections treated by debridement and implant retention (DAIR): similar long-term remission for 6 weeks as …

H Chaussade, I Uçkay, A Vuagnat, J Druon… - International Journal of …, 2017 - Elsevier
… continuing antibiotic therapy, eg for suppressive treatment. The duration of antibiotic therapy
… However, the choice of the antibiotic agents must be appropriate according to nationwide …

[HTML][HTML] Mechanical debridement with antibiotics in the treatment of chronic periodontitis: effect on systemic biomarkers―a systematic review

SL Munasur, EB Turawa, UME Chikte… - International journal of …, 2020 - mdpi.com
… There is little or no evidence that adjunctive systemic antibiotics therapy improves inflammatory
systemic biomarkers, compared to mechanical debridement alone, among adults with …

[HTML][HTML] Surgical debridement is superior to sole antibiotic therapy in a novel murine posttraumatic osteomyelitis model

JM Wagner, H Zöllner, C Wallner, B Ismer, J Schira… - PLoS …, 2016 - journals.plos.org
… be achieved by intensive debridement resulting in large critical … debridement and subsequent
antibiotic therapy or antibiotic … , Gentamicin was used for antibiotic therapy, as it is often …