Fine tuning the immune response through B7‐H3 and B7‐H4
KH Yi, L Chen - Immunological reviews, 2009 - Wiley Online Library
… against viral infections and normal hypersensitive inflammatory responses … B7-H4 may
be a fine tuner of the adaptive immune response. B7-H4 as an inhibitor of innate immunity …
be a fine tuner of the adaptive immune response. B7-H4 as an inhibitor of innate immunity …
B7-h4 expression in human melanoma: its association with patients' survival and antitumor immune response
D Quandt, E Fiedler, D Boettcher, WC Marsch… - Clinical cancer …, 2011 - AACR
… time B7-H3 and B7-H4 expression in primary and metastatic melanoma lesions. Tumor B7-H4
… To understand the functional role of tumor B7-H4, we carried out HLA-I–restricted T-cell–…
… To understand the functional role of tumor B7-H4, we carried out HLA-I–restricted T-cell–…
Potential targeting of B7‐H4 for the treatment of cancer
JR Podojil, SD Miller - Immunological reviews, 2017 - Wiley Online Library
… immune response and by a cell-mediated immune response. … , and its role in immune cell
function. The main body of work … an agonistic B7-H4 immunoglobulin fusion protein (B7-H4 Ig) …
function. The main body of work … an agonistic B7-H4 immunoglobulin fusion protein (B7-H4 Ig) …
A review of B7-H3 and B7-H4 immune molecules and their role in ovarian cancer
JM Fauci, JM Straughn Jr, S Ferrone… - Gynecologic …, 2012 - Elsevier
… that this ligand may regulate immune responses mediated by T-helper (Th) type I inflammatory
cells [9]. This review will focus primarily on B7-H3 and B7-H4 ligands, which have been …
cells [9]. This review will focus primarily on B7-H3 and B7-H4 ligands, which have been …
Possible involvement of soluble B7-H4 in T cell-mediated inflammatory immune responses
Y Kamimura, H Kobori, J Piao, M Hashiguchi… - Biochemical and …, 2009 - Elsevier
… Here, we demonstrated that B7-H4 expression in immune … expressing B7-H4 secreted soluble
B7-H4 and the serum B7-H4 … of B7-H4 in T cell-mediated inflammatory responses and the …
B7-H4 and the serum B7-H4 … of B7-H4 in T cell-mediated inflammatory responses and the …
[HTML][HTML] In vivo function of immune inhibitory molecule B7-H4 in alloimmune responses
K Yamaura, T Watanabe, O Boenisch, M Yeung… - American Journal of …, 2010 - Elsevier
… B7-H4 in T cell-mediated inflammatory immune responses (… of B7-H4 as an important
inhibitor of innate immunity through … The role of B7-H4 in alloimmune responses is poorly …
inhibitor of innate immunity through … The role of B7-H4 in alloimmune responses is poorly …
B7-H4, a molecule of the B7 family, negatively regulates T cell immunity
GL Sica, IH Choi, G Zhu, K Tamada, SD Wang… - Immunity, 2003 - cell.com
… a B7 family molecule, B7-H4, by protein sequence analysis and comparative molecular
modeling. While B7-H4 … on both humoral and cell-mediated immune responses. For example, …
modeling. While B7-H4 … on both humoral and cell-mediated immune responses. For example, …
B7-H4 overexpression impairs the immune response of T cells in human cervical carcinomas
X Wang, T Wang, M Xu, L Xiao, Y Luo, W Huang… - Human Immunology, 2014 - Elsevier
… , but no B7-H4 expression was observed in normal cervical epithelia. Aberrant B7-H4 expression
was … This indicated that B7-H4 suppressed anti-tumor immune response in the cervical …
was … This indicated that B7-H4 suppressed anti-tumor immune response in the cervical …
B7x/B7-H4 modulates the adaptive immune response and ameliorates renal injury in antibody-mediated nephritis
RD Pawar, B Goilav, Y Xia, L Herlitz… - Clinical & …, 2015 - academic.oup.com
… B7 family expressed predominantly by non-lymphoid tissues, has been shown to inhibit the
proliferation, activation and functional responses … by a robust adaptive immune response and …
proliferation, activation and functional responses … by a robust adaptive immune response and …
Antibody targeting of B7-H4 enhances the immune response in urothelial carcinoma
… cells present within healthy human bladder, with increased expression of B7-H4 in … B7-H4
expressing cells, our data show that B7-H4 is expressed in the BBN mouse model, and B7-H4 …
expressing cells, our data show that B7-H4 is expressed in the BBN mouse model, and B7-H4 …